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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(7): 3981-3991
DOI: https://doi.org/10.20546/ijcmas.2017.607.412


Molecular Characterization of Measles Virus among Children in Parts of North Western Nigeria
Abdul Fatai1*, O.S. Olonitola2, M. Aminu2 and E.D. Jatau2
1Department of Microbiology, Kaduna State University, Kaduna, Nigeria
2Department of Microbiology, Ahmadu Bello University, Zaria, Nigeria
*Corresponding author
Abstract:

Molecular characterization of measles virus among children in parts of north western Nigeria, out of 30 samples analysed for PCR with specific primers, 21 samples confirmed presence of measles virus infection. Genotype B3 strain was confirmed in four (4) samples selected from different location within the state in Northern Western Nigeria. Sokoto, Jigwa and Kaduna States,   Ten (10) IgM positive samples from each States were randomly selected and subjected to RT PCR, out of the ten (10) IgM positive samples from each state. Twenty (66.7%: 20/30) IgM positive samples shows a band with an amplicon size of 527bp. Four measles virus were subjected to sequencing and BLAST and all were genotype B3 strain. The BLAST information obtained from the queried sequences and the closest corresponding sequences from the GenBank corresponded with genotype B3 from Genbank, The phylogenetic relatedness of measles virus in this study with those in the GenBank revealed a common homology.


Keywords: Measles virus infection, Aerosolized secretions,   Systemic infection, Nasopharynx, viremia.
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How to cite this article:

Abdul Fatai, K., O.S. Olonitola, M. Aminu and Jatau, E.D. 2017. Molecular Characterization of Measles Virus among Children in Parts of North Western Nigeria.Int.J.Curr.Microbiol.App.Sci. 6(7): 3981-3991. doi: https://doi.org/10.20546/ijcmas.2017.607.412