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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(7): 3940-3947
DOI: https://doi.org/10.20546/ijcmas.2017.607.406


Multidrug Resistance Pattern in Confirmed Cases of Central Venous Catheter Blood Stream Infections in a Tertiary Care Hospital: A Prospective Study
Shilpa1 and G.P. Aaftab2*
1Medanta Mediciti, Gurgaon, India
2Navodaya Medical College Hospital and Research Centre, Raichur, India
*Corresponding author
Abstract:

Central venous access which plays an important role in the management of critically ill patients, also puts patient at the risk of central venous catheter associated bloodstream infections (CVC-BSI). These infections are difficult to treat because they are being increasingly caused by multi-drug resistant organisms. This study was carried out to determine CVC-BSI rate in Intensive Care Units of a tertiary care hospital and to identify the antibiotic resistance profile of the infectious agents involved. Distal 5cm of the central venous catheter and blood samples were collected and processed using conventional culture methods as per standard protocol. During the study of one year, 720 patients were treated by indwelling catheter, of which 36 developed bloodstream infections, amounting to a CVC_BSI rate of 7.14 per 1000 catheter days. We observed that 73.07% of the Gram negative bacteria isolated from the cases were ESBL producers, 57.69% were AmpC producers and 34.61% were Co-producers of both ESBL and AmpC. Prevention of infusate contamination and aseptic handling by healthcare personnel will play a great role in bringing down the CVC-BSI rates and curb the nuisance of spread of multi drug resistant hospital acquired infections.


Keywords: CVCBSI, Incidence rate, Antimicrobial resistance.
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How to cite this article:

Shilpa and G.P. Aaftab. 2017. Multidrug Resistance Pattern in Confirmed Cases of Central Venous Catheter Blood Stream Infections in a Tertiary Care Hospital: A Prospective Study.Int.J.Curr.Microbiol.App.Sci. 6(7): 3940-3947. doi: https://doi.org/10.20546/ijcmas.2017.607.406