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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(7): 1776-1779
DOI: https://doi.org/10.20546/ijcmas.2017.607.214


Study of Antibiotic Susceptibility Pattern in Staphylococcus aureus Isolated from Skin and Soft Tissue Infections in a Tertiary Care Hospital
Swati Rahul Dhope*, Dnyaneshwari Purushottum Ghadage, Arvind Vamanrao Bhore
Department of Microbiology, Smt. Kashibai Navale Medical College and General Hospital, Narhe, Pune-41, India
*Corresponding author
Abstract:

Staphylococcus aureus is responsible for widespread infections in the community as well as hospital settings. Rapid emergence of resistance to antibiotics is well known in this organism; particularly in the Methicillin resistant Staphylococcus aureus (MRSA). So present study was carried out to detect current trend in the antibiotic susceptibility of S. aureus isolated from skin and soft tissue infections which in turn will be helpful for choosing empirical antibiotics for these infections. The study was conducted in our tertiary care hospital during the period of January to December 2016. S. aureus isolated from all the skin and soft tissue infections were included in the study. Antibiotics tested were- penicillin, amoxiciliin-clavulanate, cefazolin, doxycycline, erythromycin, ciprofloxacin, trimethoprim-sulfamethoxazole, vancomycin and teicoplanin. Out of 320 S. aureus isolates, 138 (43.1%) were MRSA while 182 (56.9%) were methicillin sensitive Staphylococcus aureus (MSSA). Highest resistance was observed among ciprofloxacin (86.6%), penicillin (79.7%) and amoxicillin-clavulanate (78.1%). Doxycycline and trimethoprim-sulfamethoxazole had maximum sensitivity of 86.9% and 73.8% respectively. All MRSA showed 100% sensitivity to vancomycin and teicoplanin. With this sensitivity pattern, this study emphasizes that doxycycline and trimethoprim-sulfamethoxazole are the drug of choice for empirical treatment of skin and soft tissue infections caused by Staphylococcus aureus.


Keywords: Staphylococcus aureus, MRSA, Antibiotic susceptibility, Antibiotic resistance, Skin and soft tissue infections.
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How to cite this article:

Swati Rahul Dhope, Dnyaneshwari Purushottum Ghadage, Arvind Vamanrao Bhore. 2017. Study of Antibiotic Susceptibility Pattern in Staphylococcus aureus Isolated from Skin and Soft Tissue Infections in a Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 6(7): 1776-1779. doi: https://doi.org/10.20546/ijcmas.2017.607.214