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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(7): 2567-2576
DOI: https://doi.org/10.20546/ijcmas.2017.607.303


Prevalence of Mycobacterium tuberculosis in Children Suffering from Lower Respiratory Tract Infection Attending a Tertiary Care Hospital, Hyderabad
Vipparti Haritha1* and V.V. Shailaja2
1Department of Microbiology, Malla Reddy Institute of Medical Sciences,Hyderabad, Telangana state, India
2Department of Microbiology, Gandhi Medical College, Hyderabad, Telangana state, India
*Corresponding author
Abstract:

Though the declaration by the WHO of a ‘global TB emergency’ was in 1993, the emphasis has been more on adult disease. Pediatric TB was neglected, mainly due to greater challenges in diagnosis and the lower priority traditionally afforded to children by TB control programmes. As a result both research and surveillance data in the field of childhood TB have been greatly limited. Hence the present study was undertaken from 6/1/10 – 8/2/11 to know the isolation rate of Mycobacterium tuberculosis and Drug susceptibility patterns in children suffering from LRTI. 153 Gastric aspirates were collected and processed by conventional methods and anti-tubercular drug sensitivity testing was done by Proportion method. 30 isolates of Mycobacterium were obtained of which 7 isolates were Atypical Mycobacteria. All isolates of Mycobacterium tuberculosis were sensitive to Isoniazid, Rifampicin and Ethambutol. 13.6%of the strains were resistant to Streptomycin. TB in children presents particularly difficult challenges, but research priorities and advances in pediatric TB research may also provide wider insights and opportunities for TB control. Better diagnostics would probably represent the next most important step which will not only improve individual case management, but also provide a rapid detection of drug resistance.


Keywords: Gastric aspirates, Mycobacterium, Drug susceptibility
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How to cite this article:

Vipparti Haritha and Shailaja, V.V. 2017. Prevalence of Mycobacterium tuberculosis in Children Suffering from Lower Respiratory Tract Infection Attending a Tertiary Care Hospital, Hyderabad.Int.J.Curr.Microbiol.App.Sci. 6(7): 2567-2576. doi: https://doi.org/10.20546/ijcmas.2017.607.303