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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(6): 2740-2743
DOI: https://doi.org/10.20546/ijcmas.2017.606.327


Diagnostic Performance of Anti-Cyclic Citrullinated Peptide Antibodies in Rheumatoid Arthritis and Other Rheumatological Disorders
Saumya Agarwal*, Anuradha, Amiyabala Sahoo and Nandini Duggal
Department of Microbiology, Dr. Ram Manohar Lohia Hospital, New Delhi-110001, India
*Corresponding author
Abstract:

Anticyclic citrullinated peptide antibodies (anti-CCP) are considered specific markers of rheumatoid arthritis and have been included in the revised classification criteria for RA diagnosis. However, these antibodies have also been detected in patients with other rheumatological disorders is to identify the prevalence of positive anti-CCP patients in RA and non-RA rhematological diseases, to determine the diagnostic value of anti-CCP for the diagnosis of RA. An observational study was carried out in department of Microbiology at Dr. Ram Manohar Lohia Hospital, New Delhi over a period of 1 year. In 343 RA and 52 other rheumatological disease patients anti-CCP antibodies were determined. Anti-CCP antibodies were detected in 277 of the 395 patients. The prevalence of anti-CCP was 274/373 in RA, 1/4in patients with spondyloarthritis, 1/4 in patients with juvenile rheumatoid arthritis and 1/15 in patients with systemic lupus erythematosus. Anti-CCP are a hallmark of RA, but may be observed in other inflammatory, systemic, or rheumatological diseases.


Keywords: Rheumatoid arthritis, Diagnosis, anticyclic citrullinated peptide antibodies, Sensitivity, Specificity, Diagnostic value
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How to cite this article:

Saumya Agarwal, Anuradha, Amiyabala Sahoo and Nandini Duggal. 2017. Diagnostic Performance of Anti-Cyclic Citrullinated Peptide Antibodies in Rheumatoid Arthritis and Other Rheumatological Disorders.Int.J.Curr.Microbiol.App.Sci. 6(6): 2740-2743. doi: https://doi.org/10.20546/ijcmas.2017.606.327