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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2019) [Effective from January 1, 2019]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(3): 860-864
DOI: http://dx.doi.org/10.20546/ijcmas.2016.503.099


Biosynthesis of Clot Busting Fibrinolytic Enzyme from Aspergillus japonicum by Supplementing Carbon Sources
Saroj Yadav1 and K. G. Siddalingeshwara2*
1Research and Development, Bharathiar University, Coimbatore
2Scientific & Industrial Research Centre, Bangalore
*Corresponding author
Abstract:

Fibrinolytic enzymes that dissolve blood clots and show promise for thrombosis therapy have been successfully identified from various sources. A wide range of microorganisms has been screened for their fibrinolytic properties. The Aspergillus Japonicum KGSS 05 were isolated from different soils from different regions of  Karnataka and screened for fibrinolytic activity by plate assay. The potential strain Aspergillus Japonicum KGSS 05 were  used for  the enhance the biosynthesis of fibrinolytic enzyme by supplementation of carbon sources were employed in range of 0.25% to 1.25%. The carbon source were supplemented are glucose, sucrose and maltose. Among the carbon source the glucose showed better yield of 246 IU fibrinolytic enzyme production and maltose and  sucrose showed 123 IU and 176 IU.     


Keywords: Carbon source, Clot buster drug, Fibrin carbon source, Aspergillus japonicum
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How to cite this article:

Saroj Yadav and  Siddalingeshwara, K. G. 2016. Biosynthesis of Clot Busting Fibrinolytic Enzyme from Aspergillus japonicum by Supplementing Carbon Sources.Int.J.Curr.Microbiol.App.Sci. 5(3): 860-864. doi: http://dx.doi.org/10.20546/ijcmas.2016.503.099