National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The present study was conducted to detect the most common bacterial pathogens associated with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and their antibiogram in Egyptian patients and to assess the quantitative culture technique of washed sputum specimens. Thirty patients diagnosed as AECOPD by pulmonary functions tests and clinical findings were subjected to physical examination, chest x-ray, routine laboratory tests, as well as direct and quantitative culture of washed sputum specimens. Potential bacterial pathogens above the cutoff count were isolated in 66.6% of studied patients. The most common isolated bacterial pathogen was Streptococcus pneumoniae (43.3%) followed by methicillin-resistant Staphylococcus aureus (MRSA) (10%), Haemophilus influenzae (6.7%) and finally Acinetobacter spp and Moraxella catarrhalis (3.3% for each). Organisms were mostly sensitive to quinolones followed by ceftriaxone. Neither leucocytosis nor CRP was a good predictor of bacterial infections. There was a good correlation between gram-stained smear results and culture results. The wash technique improved the sputum smear and culture results. Bacterial infections play an important role in AECOPD. Quinolones are good therapeutic options. The wash technique could be used to improve the diagnostic value of sputum specimens.
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