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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(6): 921-926
DOI: https://doi.org/10.20546/ijcmas.2017.606.108


Study of Antibiotic Sensitivity Pattern of Staphylococcus aureus and Comparison of Cefoxitin and Oxacillin Discs for Detection of MRSA in a Tertiary Care Hospital
V. Aruna1*, S. Nirmala1 and K.R. Rajendran2a
1Department of Microbiology, Government Mohan Kumaramangalam Medical College,Salem, Tamil Nadu, India
2Department of Microbiology, Coimbatore Medical College, Coimbatore, Tamil Nadu, India
*Corresponding author
Abstract:

Staphylococcus aureus is the commonly encountered pathogen isolated from clinical specimens. Methicillin resistant Staphylococcus aureus (MRSA) causes variety of human infections resulting in high rate of mortality and morbidity. The aim of the study was to screen for MRSA by disc diffusion method using cefoxitin and oxacillin discs and to determine antimicrobial susceptibility and resistance of Staphylococcus aureus. Two hundred Staphylococcus aureus were isolated from samples like pus, blood, sputum, vaginal swab, urine and body fluids received in microbiology department of Coimbatore medical college hospital. They were confirmed by microscopy, culture and biochemical reactions. MRSA were detected by disc diffusion test using cefoxitin (30μg) and oxacillin (1μg) discs. Majority of Staphylococcus aureus were isolated from pus samples (87.5%). Isolated Staphylococcus aureus strains were highly sensitive to linezolid (100%) and vancomycin (99%) and 100% resistant to penicillin. Cefoxitin disc detected higher percentage (26%) of MRSA than oxacillin disc (24%). Detection of MRSA is considered as very important for treating patients and to prevent its spread.


Keywords: MRSA, Cefoxitin, Oxacillin, Biochemical.
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How to cite this article:

Aruna, V., S. Nirmala and Rajendran, K.R. 2017. Study of Antibiotic Sensitivity Pattern of Staphylococcus aureus and Comparison of Cefoxitin and Oxacillin Discs for Detection of MRSA in a Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 6(6): 921-926. doi: https://doi.org/10.20546/ijcmas.2017.606.108