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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(5): 2322-2327
DOI: https://doi.org/10.20546/ijcmas.2017.605.259


Antimicrobial Drug Discovery: Evident Shifting from Terrestrial to Marine Micro-organisms
R.D. Singh*, S.K. Mody, H.B. Patel, Sarita Devi, V.N. Sarvaiya, H.A. Patel and B.R. Patel

Department of Pharmacology and Toxicology, CoVSc and AH, SDAU,

Sardarkrushinagar, Gujarat -385506, India
*Corresponding author
Abstract:

Marine derived micro-organisms secrete precious bioactive molecules in traceable amount as their secondary metabolites. These bio-molecules can be developed into antimicrobial agents, using modern tools of molecular biology and drug discovery. Exhaustion of terrestrial sources and demand of newer class of antibiotics due to ever-increasing resistance level in existing antimicrobial drugs, led a paradigm shift from land to ocean for discoveries of such agents. Marine bacteria, fungi and algae are potential sources of novel antimicrobial drugs. Many such agents are identified worldwide including India. Huge cost of marine bioprospecting and non-culturability of marine microbes are the major hurdles in marine drug development which emphasized need of public-private partnerships and advanced technologies like metagenomic tools, genetic recombinant techniques and chemoenzymatic synthesis.


Keywords: Antimicrobial drugs, Marine bioprospecting, Marine drug discovery, Micro-organisms
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How to cite this article:

Singh R.D., S.K. Mody, H.B. Patel, Sarita Devi, V.N. Sarvaiya, H.A. Patel and Patel B.R. 2017. Antimicrobial Drug Discovery: Evident Shifting from Terrestrial to Marine Micro-organisms.Int.J.Curr.Microbiol.App.Sci. 6(5): 2322-2327. doi: https://doi.org/10.20546/ijcmas.2017.605.259