National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The present study was designed to investigate the antibacterial and antifungal activity of aqueous, methanolic, and ethanolic leaf extracts of Moringa oleifera. The extracts were screened using the disc diffusion method against selected bacterial and fungal pathogens. The leaf extracts exhibited broad-spectrum antimicrobial activity. For antibacterial activity at a concentration of 30 mg/mL, zones of inhibition ranged from (10.0–17.0 mm) for the aqueous extract, (9.0–19.0 mm) for the methanolic extract, and (0–10.0 mm) for the ethanolic extract. The methanolic extract showed the highest antibacterial activity against the tested enteropathogenic bacteria. For antifungal activity, the ethanolic extract demonstrated the greatest inhibition, with zones ranging from (16–20 mm), while the aqueous extract showed the least activity (7.0–10.0 mm). The extracts showed varying degrees of effectiveness against bacterial strains such as Staphylococcus aureus, Klebsiella species, Shigella dysenteriae, Bacillus cereus, Escherichia coli, Proteus species, Vibrio cholerae, Salmonella typhi, Enterococcus sp., Providencia stuartii and fungal isolates including Fusarium sp., Alternaria sp., Pullarium sp., Candida albicans, and Curvularia sp. suggesting that Moringa oleifera leaf extracts possess significant antimicrobial potential, with activity influenced by the extraction solvent.
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