National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Natural products derived from microbes, plants, and animals offer a broad variety of molecules and chemical compounds. Natural products are not only one of the most important sources for innovative drug development for animal and human health, but they are also an inspiration for synthetic biology and chemistry scientists towards the discovery of new bioactive compounds and pharmaceuticals. This is particularly relevant in the current context, where antimicrobial resistance has risen as a global health problem. Phytochemical screening of T catappa L plant leaf was done in hot water, cold water, ethanol and methanol extract. Tannin, quinine, terpenoid, flavonoid, steroid, alkaloid, cardiac glycoside, glycoside, volatile oils, etc were the phytoconstituents found in plants. The existence of these secondary metabolites has been noted to contribute to the antimicrobial activity exhibited by plants. The phytoconstituents present in the plant extract showed an effect on bacterial and fungal culture. This study utilized two bacterial cultures, Bacillus cereus and Escherichia coli, to evaluate the extract's efficacy. E. coli displayed the greatest inhibition with methanol extract at 22 mm. Bacillus cereus exhibited the highest inhibition zone with methanol at 20.66 mm. The cultures of Aspergillus terreus exhibited the greatest zone of inhibition (21 mm) for the methanol extract, using the Agar well diffusion method while Disc Diffusion method shown highest zone of inhibition for ethanol 17 mm. Aspergillus flavus exhibited the greatest zone of inhibition at 15 mm for ethanol, using the agar well diffusion method. The Disc diffusion method displayed the greatest zone of inhibition with cold water at 11 mm. The findings from both the Disc and well diffusion methods indicate that the well diffusion method is superior for antifungal research. Hence these plants could be used to develop drugs and also may be effective against fungi and bacteria.
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