National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Diabetic foot infections (DFIs) are serious public health issues. The accurate knowledge of the organisms and their susceptibility pattern would improve rational use of antibiotics and prevent resistance. The aim was to investigate the organism profile and antimicrobial susceptibility pattern of microbes in DFIs. A retrospective, cross sectional study was conducted for a period of 1 year at the Department of General Surgery, Malabar Medical College Hospital and research centre, Kerala, India. During this period, 106 patients having DFIs admitted in the general surgery wards were tracked from the hospital data management system Samples of pus, swab and whole blood from the patients were tested for organisms and their antibiotic susceptibity. Consecutive sampling technique was used. Antimicrobial susceptibility test was performed by disc diffusion techniques according to Clinical and Laboratory Standards Institute guidelines. Of the 106 specimens of the diabetic foot lesions, culture showed polymicrobial growth in 34.9% (37/106), monomicrobial growth in 50.9% (54/106), and no growth in 14.2% (15/106). Microbiological evaluation of diabetic foot ulcer infections showed that the prevalence of Gram-negative organisms (79.10%, 106/134) and Gram-positive organisms (20.89%, 28/134). Klebsiella species was the most frequent pathogens (19.40% [26/134]). Staph aureus (13 [46.42%]) isolates were the bacterial species most commonly isolated among the Gram-positive bacteria. Staph aureus isolates were 100% sensitive to rifampicin and daptomycin. Staph haemolyticus showed 100% sensitivity to tigecycline, vancomycin, and linezolid. E. faecalis isolates were 100% susceptible to linezolid and daptomycin. The current study shows that the prevalence of Gram-negative organisms was greater than that of Gram-positive organisms. DFU was shown to be more prevalent in men than in women. In our study, a greater percentage of monomicrobial infections was found. The DFU was significantly higher in patients with uncontrolled diabetes. Klebsiella species were the most common microorganisms found in the diabetic foot ulcer patients. The study emphasizes the need for preventing the DFI by stricter diabetic control measures and rational use of antibiotics with correlation to organisms and their susceptibility pattern.
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