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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 14, Issue:11, November, 2025

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
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Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2025.14(11): 269-274
DOI: https://doi.org/10.20546/ijcmas.2025.1411.027


Molecular Characterization of Sheep Pox Outbreak in the State of Uttar Pradesh in India
Himanshu Agarwal1, A. P. Garg2*, Surendra Upadhyay3 and Amit Kumar3
1School of Biotechnology and Life Sciences, Shobhit Institute of Engineering & Technology, Deemed to-be-University, NH-58, Modipuram, Meerut-250110, UP, India. 2Swami Vivekanand Subharti University, NH-58, Subhartipuam, Meerut-250005, UP, India. 3College of Biotechnology, Sardar Vallabh bhai Patel University of Agriculture & Technology (SVPUAT), NH-58, Modipuram, Meerut-250110, UP, India
*Corresponding author
Abstract:

Sheep pox virus is widespread in India and clinical cases are reported across the country throughout year, particularly during extreme climatic conditions. In India sheep rearing is associated with a particular community and being land less and economically weaker, owners used to migrate one to another place for grazing of their flocks. Such animal husbandry practices make these animals exposed and susceptible to viral diseases. Thus, the thorough investigations of outbreaks are essential to establish linkage and lineages of prevailing virus and also to find out presence of any new strain. The current report investigated an outbreak of sheep pox during April to September, 2024 in Uttar Pradesh. The samples were confirmed through P32gene based amplification and subjected to sequencing of 4 representative samples collected from 4 different villages. Phylogenetic analysis of the full-length P32gene revealed homology with sheep pox isolates previously reported from various places of India and subsequently with neighboring countries. It suggested high lineage-specificity of Indian sheep pox virus and its correlation with the original host. Thus, continuous and proper vaccination of existing sheep population with homologous vaccine strain is recommended to prevent and control it’s incidences as well as outbreaks.


Keywords: Sheep pox, Outbreak; P32gene; phylogenetic analysis


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How to cite this article:

Himanshu Agarwal, A. P. Garg, Surendra Upadhyay and Amit Kumar. 2025. Molecular Characterization of Sheep Pox Outbreak in the State of Uttar Pradesh in India.Int.J.Curr.Microbiol.App.Sci. 14(11): 269-274. doi: https://doi.org/10.20546/ijcmas.2025.1411.027
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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