A Study on Antimicrobial Susceptibility Pattern among Klebsiella species Isolated From Various Clinical Samples in a Tertiary Care Hospital
S. Gowrisankar*, S. Ravikumar, A. Saravanakumar, K. Vishwapriya and Varshini
Chengalpattu Medical College, Tamil Nadu, India
*Corresponding author
Abstract:
In recent years due to the indiscriminate use of antimicrobials, Klebsiella species have emerged as important healthcare-associated pathogens. Multidrug resistance is increasing among Klebsiella species and hence detection of their antimicrobial susceptibility pattern and resistant mechanism is a crucial infection control issue because they are often associated with extensive antibiotic resistance and treatment failure. From August 2023 to July 2024, 150 Klebsiella species were isolated from various clinical specimens. Those isolates were subjected to antimicrobial susceptibility testing, detection of ESBL, AmpC and Carbapenemase activity and AmpC resistant gene. Out of 150 Klebsiella species isolated 34 were showed ESBL production, 16 showed AmpC production, 25 isolates showed carbapenemase production. 12 isolates found to have AmpC resistant gene. This study highlights the high prevalence multidrug resistance among Klebsiella species.
Keywords: Multidrug resistance, ESBL, AmpC, Carbapenemase
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How to cite this article:
Gowrisankar S., S. Ravikumar, A. Saravanakumar, K. Vishwapriya and Varshini. 2025. A Study on Antimicrobial Susceptibility Pattern among
Klebsiella Species Isolated From Various Clinical Samples in a Tertiary Care Hospital.
Int.J.Curr.Microbiol.App.Sci. 14(11): 185-194. doi:
https://doi.org/10.20546/ijcmas.2025.1411.019
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National Academy of Agricultural Sciences (NAAS) 
