National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Prosthetic joint infections (PJI) represent a severe complication following arthroplasty, contributing significantly to patient morbidity and substantial healthcare expenditures. This study aimed to characterize the microbiological profile of prosthetic joint infections at a tertiary care hospital. A prospective evaluation was conducted on 66 in-patient samples from individuals admitted to the orthopedic department with a history of PJI between November 2024 and May 2025. Periprosthetic tissue samples were collected and processed according to standard microbiological protocols. Among 66 confirmed PJI cases, a culture positivity rate of 56% was observed. Gram-positive cocci were the predominant pathogens (n=25, 37.8%), including MSSA (n=5, 7.5%), MRSA (n=6, 9%), Staphylococcus other than S.aureus group SoSA (n=8, 12%), Streptococcus species (n=4, 6.06%), and Enterococcus species (n=2, 3.03%). Gram-negative bacilli accounted for 18.1% of infections (n=12), with Enterobacter cloacae complex (n=4, 6.06%), E. coli (n=3, 4.5%), P. aeruginosa (n=3, 4.5%), S. marcescens (n=1, 1.5%), and K. pneumoniae (n=1, 1.5%) being isolated. The findings of this study highlight the significant prevalence of both gram-positive cocci, particularly staphylococcal species, and gram-negative bacilli in prosthetic joint infections within our tertiary care setting. This detailed bacteriological profile is crucial for guiding empirical antibiotic therapy and developing targeted infection control strategies to improve patient outcomes and reduce the burden of PJI.
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