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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here
ICV 2023: 95.56
Index Copernicus ICI Journals Master List 2023 - IJCMAS--ICV 2023: 95.56
For more details click here
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Original Research Articles                      Volume : 14, Issue:10, October, 2025
PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
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Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
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Int.J.Curr.Microbiol.App.Sci.2025.14(10): 151-157
DOI: https://doi.org/10.20546/ijcmas.2025.1410.015


Effect of Vincholine Supplementation on CHDH, PEMT-1, BHMT and MAT1 Gene Regulation in Commercial Broilers
Jaiguru Kadam1, Neerad Khuje1, Akanksha V. Dhende2 and Hitesh N. Pawar2*
1Vinayak Ingredients India Pvt. Ltd, Mumbai, Maharashtra, India 2Verity Vet Laboratories Pvt. Ltd., Pune, Maharashtra, India
*Corresponding author
Abstract:

Choline is an essential nutrient for broiler chickens, vital for lipid metabolism, methyl group donation, and liver health. This study examined the impact of Vincholine, a natural choline source developed by Vinayak Ingredients (India) Pvt. Ltd., on the expression of key genes—CHDH, PEMT-1, BHMT, and MAT1 in broilers. Birds were assigned to three groups: a control group fed a basal diet with synthetic choline chloride, and two treatment groups receiving 300 g/tonne (T1) and no choline chloride (T2), respectively, over 42 days. Gene expression was measured via real-time PCR from liver samples. The T1 group showed significantly lower expression of all four genes compared to the T2 group, indicating better choline availability and utilization. Expression levels in T1 were close to those of healthy birds, suggesting a hepatoprotective effect. These results suggest Vincholine supplementation may support liver health and improve choline metabolism in broiler production.


Keywords: Broiler chickens, Choline, Vincholine, gene expression, liver

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How to cite this article:

Jaiguru Kadam, Neerad Khuje, Akanksha V. Dhende and Hitesh N. Pawar. 2025. Effect of Vincholine Supplementation on CHDH, PEMT-1, BHMT, and MAT1 Gene Regulation in Commercial BroilersInt.J.Curr.Microbiol.App.Sci. 14(10): 151-157. doi: https://doi.org/10.20546/ijcmas.2025.1410.015
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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