Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2023 - IJCMAS--ICV 2023: 95.56 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020] For more details click here

Login as a Reviewer


See Guidelines to Authors
Current Issues
Download Publication Certificate

Original Research Articles                      Volume : 14, Issue:9, September, 2025

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2025.14(9): 54-57
DOI: https://doi.org/10.20546/ijcmas.2025.1409.006


Microbial Metabolism and Virulence
School of Agriculture and Allied Sciences, The Neotia University, Sarisa, West Bengal, India
*Corresponding author
Abstract:

Metabolism, an important activity is essential for microbial population build up. This activity is joined with metabolism interfering virulence factors leading to dominance of one species in a mixed culture. In a linear relation, more microbial growth leads to more infective propagule (I.P.) count, and mixed culture activity is seen in many environments including organic matter decomposition. The present work will be studying the interaction between metabolism, virulence and I.P. count of microorganisms, and will be emphasizing on the understandings and advancements between metabolism and virulence.


Keywords: Metabolism, Virulence, Infective Propagule Count


References:

Aguilar-Paredes, A., Valdés, G., Araneda, N., Valdebenito, E., Hansen, F., Nuti, M., (2023). Microbial community in the composting process and its positive impact on the soil biota in sustainable agriculture. Agronomy 13, 542. https://doi.org/10.3390/agronomy13020542

Ardestani, M.M., Kukla, J., Cajthaml, T., Baldrian, P., Frouz, J., (2025). Microbial diversity drives decomposition more than advantage of home environment-evidence from a manipulation experiment with leaf litter. Microorganisms 13(2), 351. https://doi.org/10.3390/microorganisms13020351 . PMID: 40005718; PMCID: PMC11858187

Bidondo, L.F., Colombo, R., Bompadre, J., Benavides, M., Scorza, V., Silvani, V., Pérgola, M., Godeas, A., (2016). Cultivable bacteria associated with infective propagules of arbuscular mycorrhizal fungi. Implications for mycorrhizal activity. Applied Soil Ecology 105, 86-90. https://doi.org/10.1016/j.apsoil.2016.04.013.

Cate, J.D., Sullivan, Y.Z., King, M.D. (2024). Inhibition of Microbial Growth and Biofilm Formation in Pure and Mixed Bacterial Samples. Microorganisms 12, 1500. https://doi.org/10.3390/microorganisms12071500

Forsmark, B., Bizjak, T., Nordin, A., Rosenstock, N.P., Wallander, H., Gundale, M.J., (2024). Shifts in microbial community composition and metabolism correspond with rapid soil carbon accumulation in response to 20 years of simulated nitrogen deposition. Sci Total Environ 918, 170741. https://doi.org/10.1016/j.scitotenv.2024.170741.  Epub 2024 Feb 6. PMID: 38325494.

Gonzalez, J.M., Aranda, B., (2023). Microbial Growth under Limiting Conditions-Future Perspectives. Microorganisms. 11(7), 1641. https://doi.org/10.3390/microorganisms11071641 . PMID: 37512814; PMCID: PMC10383181

Hardie, K., (2019). Where bacterial metabolism and virulence intersect. https://microbiologysociety.org/publication/past-issues/metabolism-health-and-disease/article/where- bacterial-metabolism-and-virulence-intersect.html Accessed 22 August 2025

Hasenoehrl, E.J., Wiggins, T.J., Berney, M., (2021). Bioenergetic Inhibitors: Antibiotic Efficacy and Mechanisms of Action in Mycobacterium tuberculosis. Front Cell Infect Microbiol 10, 611683. https://doi.org/10.3389/fcimb.2020.611683

Jiao, W., Liu, X., Li, Y., Li, B., Du, Y., Zhang, Z., Chen, Q., Fu, M., (2022). Organic acid, a virulence factor for pathogenic fungi, causing postharvest decay in fruits. Molecular Plant Pathology 23, 304–312. https://doi.org/10.1111/mpp.13159

Lively, C.M., (2005). Evolution of virulence: coinfection and propagule production in spore-producing parasites. BMC Evol Biol 5, 64. https://doi.org/10.1186/1471-2148-5-64

Nasslahsen, B., Prin, Y., Ferhout, H., Smouni, A., Duponnois, R., (2022). Mycorrhizae helper bacteria for managing the mycorrhizal soil infectivity. Front Soil Sci 2, 979246. https://doi.org/10.3389/fsoil.2022.979246

Pajon, C., Fortoul, M.C., Diaz-Tang, G., Marin Meneses, E., Kalifa, A.R., Sevy, E., Mariah, T., Toscan, B., Marcelin, M., Hernandez, D.M., Marzouk, M.M., Lopatkin, A.J., Eldakar, O.T., Smith, R.P., (2023). Interactions between metabolism and growth can determine the co-existence of Staphylococcus aureus and Pseudomonas aeruginosa. Elife 12, e83664. https://doi.org/10.7554/eLife.83664

Raihan, T., Rabbee, M.F., Roy, P., Choudhury, S., Baek, K.-H., Azad, A.K., (2021). Microbial Metabolites: The Emerging Hotspot of Antiviral Compounds as Potential Candidates to Avert Viral Pandemic Alike COVID-19. Front Mol Biosci 8, 732256. https://doi.org/10.3389/fmolb.2021.732256

Samantaray, A., Chattaraj, S., Mitra, D., Ganguly, A., Kumar, R., Gaur, A., Mohapatra, P.K.D., Santos- Villalobos, S.L., Rani, A., Thatoi, H., (2024). Advances in microbial based bio-inoculum for amelioration of soil health and sustainable crop production. Curr Res Microb Sci 7, 100251. https://doi.org/10.1016/j.crmicr.2024.100251.  

Somerville, G.A., Proctor, R.A., (2009). At the crossroads of bacterial metabolism and virulence factor synthesis in Staphylococci. Microbiol Mol Biol Rev 73(2), 233-48. https://doi.org/10.1128/MMBR.00005-09. PMID: 19487727; PMCID: PMC2698418.

Yang, H., Ma, L., Fu, M., Li, K., Li, Y., Li, Q., (2023). Mechanism analysis of humification coupling metabolic pathways based on cow dung composting with ionic liquids. J Environ Manage 325(Pt A), 116426. https://doi.org/10.1016/j.jenvman.2022.116426. Epub 2022 Oct 11. PMID: 36240639.

Bhagwat, A., Haldar, T., Kanojiya, P., & Saroj, S. D. (2025). Bacterial metabolism in the host and its association with virulence. Virulence, 16(1), Article 2459336. https://doi.org/10.1080/21505594.2025.2459336


Download this article as Download

How to cite this article:

Susinjan Bhattacharya. 2025. Microbial Metabolism and Virulence.Int.J.Curr.Microbiol.App.Sci. 14(9): 54-57. doi: https://doi.org/10.20546/ijcmas.2025.1409.006
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

Citations