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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 14, Issue:7, July, 2025

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2025.14(7): 214-220
DOI: https://doi.org/10.20546/ijcmas.2025.1407.026


Identification of Bioactive Antifungal Metabolites from Melia azadirach L. via GC–MS Profiling for Sustainable Management of Papaya Fungal Diseases
Varsha N. Rawade and Ashok R. Tuwar*
Department of Botany, Art's Commerce and Science College, Sonai, Tehsil Newasa, Dist. Ahilyanagar (MS), India
*Corresponding author
Abstract:

This study aims to identify antifungal phytochemicals through GC-MS analysis to evaluate their potential applications from Melia azedarach L. leaf extract (ethanolic). The phytochemical profile of the extract was analyzed using Gas Chromatography-Mass Spectrometry (GC/MS). The presence of various bioactive constituents, including alkaloids, flavonoids, tannins, saponins, glycosides, and terpenoids, was identified. Six key compounds, including Decane, Squalene, Eicosane, a Benzenepropanoic acid derivative, Phytol, and Hexadecanoic acid ester, were identified. These compounds are documented in the literature for their capacity to disrupt fungal membranes, inhibit spore germination, and function as antioxidants, thereby enhancing the antifungal potential of M. azadirach. The broad-spectrum bioefficacy of this plant not only supports its traditional medicinal applications but also underscores its potential in sustainable disease management strategies.


Keywords: Melia azedarach L, GC–MS profiling, bioactive metabolites, antifungal compounds


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How to cite this article:

Varsha N. Rawade and Ashok R. Tuwar. 2025. Identification of Bioactive Antifungal Metabolites from Melia azadirach L. via GC–MS Profiling for Sustainable Management of Papaya Fungal Diseases.Int.J.Curr.Microbiol.App.Sci. 14(7): 214-220. doi: https://doi.org/10.20546/ijcmas.2025.1407.026
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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