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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 14, Issue:6, June, 2025

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2025.14(6): 166-173
DOI: https://doi.org/10.20546/ijcmas.2025.1406.015


Emerging Co-Infection Patterns of Dengue and Chikungunya Virus in A Tertiary Care Hospital in Maharashtra, India
Shreya Dutta1*, Pankaj A. Joshi1, Neeta Jangale1 and Vanita A. Kulkarni2
1Department of Microbiology, Government Medical College Miraj, Sangli (dist.),  Maharashtra – 416410, India
2Department of Microbiology, Dr. Ashok Kulkarni Hospital Miraj, Sangli, India
*Corresponding author
Abstract:

The healthcare system in India faces formidable challenges with mosquito-borne viral diseases. The tropical climate twined with dense population serves as a breeding ground of the Aedes mosquito, the vector for the communicable diseases, dengue and chikungunya. The Government of India has a standard protocol for treatment of Dengue but same must also be available for chikungunya. Cases become complicated by underdiagnosed co-infections i.e. when both the viruses are present in the patient and either both or any one goes unnoticed. Prevalence of such cases are on the rise as we have found from the patients visiting our hospital. This research specifically targets the western Maharashtra region, aiming to find the serological prevalence and pattern of dengue and chikungunya co-infections in comparison to mono-infections. Successful outcomes from this research may help to redesign the healthcare protocols and contribute significantly to redefine diagnostic strategies, to address the impact of dengue and chikungunya in western Maharashtra. This period of study was from May 2022 to April 2023. Blood samples (~2-5ml) were received in the Viral Research and Diagnostic Laboratory, Dept. of Microbiology from cases suspected of dengue or chikungunya. The patients' serum was tested using the ICMR-NIV provided IgM Capture ELISA kits for dengue/chikungunya. The records of the reports and patient details from VRDL, Dept. of Microbiology was collected and analyzed. Data analysis was performed using MS-Excel to prepare figures and tables. During the study period, a total of 1624 samples were tested for dengue/ chikungunya and coinfection. Out of 1624 samples tested, 271 samples were tested for dengue and chikungunya coinfection. Out of the 271 samples tested for coinfection, 27 (9.96%) were found to be positive. Among the 27 coinfected patients’ sample, 11 were found to be male (40.74%) and 16 were female (59.26%). The age group of 31-40 years showed the highest coinfection rate (37.03%). Month wise data showed the highest coinfection rate in the month of August (18.5%) i.e., in monsoon, which was a demographic observation. Clear guidelines must be laid out to create awareness amongst patient population, to increase the number of testing for DENV and CHIKV. Strict surveillance must be ensured for high-risk population with special emphasis on the monsoon months. Detailed studies must be performed with coinfected patients to understand the nature of viral coinfection and the possibility of any new emergent/mutant virus.


Keywords: Dengue, Chikungunya, IgM Capture ELISA, Coinfection


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How to cite this article:

Shreya Dutta, Pankaj A. Joshi, Neeta Jangale and Vanita A. Kulkarni. 2025. Emerging Co-Infection Patterns of Dengue and Chikungunya Virus in A Tertiary Care Hospital in Maharashtra, India.Int.J.Curr.Microbiol.App.Sci. 14(6): 166-173. doi: https://doi.org/10.20546/ijcmas.2025.1406.015
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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