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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 14, Issue:4, April, 2025

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2025.14(4): 189-199
DOI: https://doi.org/10.20546/ijcmas.2025.1404.022


Formulation and Characterization of Novel Medicated Jelly from Momordica cymbalaria Hook F- A Promising Natural Approach for Diabetes Management
K. Devaki Devi1, C. Pavan Kumar1, Mukta Dixit2, H. S. Aishwarya2, Savithri Bhat2, B. Mahonara Reddy1, P. Akbar Basha1 and E. Sreedevi1*
1Department of Botany, Government College (A), Ananthapuramu, A.P., India 2Department of Biotechnology, BMS College of Engineering (A), Bengaluru, Karnataka, India
*Corresponding author
Abstract:

This study investigates the latent capacities related to the antidiabetic properties of Momordica cymbalaria, a traditional medicinal plant which is native to India and Southeast Asia, characterized by its rich phytochemical profile, which includes charantin, saponins, flavonoids, and phenolics. There is a growing interest in natural, plant-based therapeutic alternatives as there is increasing global prevalence of diabetes mellitus (DM) and the limitations of conventional synthetic drugs that show adverse effects and long-term toxicity. M. cymbalaria has historically been used in traditional medicine to manage diabetes due to its hypoglycemic and antioxidant properties. This research focuses on developing a medicated jelly formulation incorporating M. cymbalaria extracts to enhance bioavailability, improve patient compliance, and facilitate ease of administration, particularly in pediatric and geriatric populations. The jelly matrix provides a palatable, fast-dissolving delivery system that effectively delivers bioactive compounds. The formulation is characterized by its physicochemical properties, stability, and bioactivity, aiming to establish a safe, sustainable, and natural approach to diabetes management. Overall, this work highlights M. cymbalaria’s potential as a promising natural antidiabetic agent and demonstrates the feasibility of delivering plant-based therapeutics via innovative dosage forms, such as medicated jellies. This integrative approach combines traditional knowledge with modern pharmaceutical technology to address unmet needs in diabetes therapy.


Keywords: Momordica cymbalaria, antidiabetic, herbal medicine, medicated jelly, natural therapy, phytochemicals, diabetes management


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How to cite this article:

Devaki Devi, K., C. Pavan Kumar, Mukta Dixit, H. S. Aishwarya, Savithri Bhat, B. Mahonara Reddy, P. Akbar Basha and and Sreedevi, E. 2025. Formulation and Characterization of Novel Medicated Jelly from Momordica cymbalaria Hook F- A Promising Natural Approach for Diabetes ManagementInt.J.Curr.Microbiol.App.Sci. 14(4): 189-199. doi: https://doi.org/10.20546/ijcmas.2025.1404.022
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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