National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Kartagener syndrome (KS) is a rare genetic disorder of autosomal recessive inheritance which is manifested by the classical triad of bronchiectasis, chronic sinusitis, and situs inversus along with infertility in males and reduced fertility in females due to impaired or defective ciliary movement and comes under the types of primary ciliary dyskinesia (PCD). This study aims to contribute to the incidence of Kartagener syndrome by reporting this rare genetic disorder. We enlighten a case of a 65-year-old female, a resident of Aligarh, U.P., India, who presented with recurrent episodes of exacerbation of chest infection and sinusitis. After evaluating the patient through history, general physical, systemic examination, and investigation we found the classical triad of bronchiectasis, situs inversus, and chronic sinusitis, and diagnosed the case as Kartagener syndrome. Reporting such cases in a given geographical area helps in the diagnosis of such rare diseases, as one can keep them in the differentials of recurrent chest infections. Early diagnosis of such disorders prevents patients as well as the health care system from the unnecessary burden of repeated investigation and helps in better outcomes and may result in improved quality of life.
Afzelius BA, Eliasson R. Male and female infertility problems in the immotile-cilia syndrome. Eur J Respir Dis Suppl. 1983; 127:144-7.
Al Razi Abu Bakar Mohammad Bin Zakariya. (1999) “Maqal Fi abdal al Adwiya al Mustamal fi al Tib wa ai Ilaj”(English Translation). 1st ed. New Delhi. CCRUM Ministry of Health and Family Welfare;Pp: 53-54,95-96.
Ali Syed Safiuddin. “Unani AdviaMufrada”.(1993) New Delhi. Taraqqi Urdu Bureau; Pp:99-100.
Anonymous. (1956) “The Wealth of India”. Vol IV. New Delhi. Council of Scientific and Industrial Research;Pp:151-154
Anonymous. (2011). National Formulary of Unani Medicine. Vol VI. New Delhi. CCRUM Ministry of Health and Family Welfare; Pp:61
Barthwal MS. Kartagener's syndrome in a fertile male - An uncommon variant. Lung India. 2006; 23:123-5. https://doi.org/10.4103/0970-2113.44404
Camner P, Mossberg B, Afzelius BA. Evidence of congenitally nonfunctioning cilia in the tracheobronchial tract in two subjects. Am Rev Respir Dis. 1975;112:807–9. https://doi.org/10.1164/arrd.1975.112.6.807
Dixit R, Dixit K, Jindal S, Shah KV. An unusual presentation of immotile-cilia syndrome with azoospermia: Case report and literature review. Lung India. 2009; 26:142-5. https://doi.org/10.4103/0970-2113.56352
Eliasson R, Mossberg B, Camner P, Efzelius BA. The immotile cilia syndrome: A congenital ciliary abnormality as an etiologic factor in chronic airway infections and male sterility. N Engl J Med. 1977;297:1–6. https://doi.org/10.1056/nejm197707072970101
Gupta S, Handa K, Kasliwal R, Bajpai P. A case of Kartagener’s syndrome: Importance of early diagnosis and treatment. Indian J Hum Genet 2012;18:263-7. https://doi.org/10.4103/0971-6866.100787
Kabeeruddin. YNM. Makhzanul Mufridat. New Delhi. CCRUM Ministry of Health and Family Welfare; Pp;,86-87,101-102,116-118,321,549-551.
Kartagener M. Zur Pathologie der Bronchiektasien: Bronchiektasienbei Situs visceruminvertus. Beitr Klin Tuberk. 1933;83:489–501.
Khan Mohd Azam. Muheet e Azam (Urdu Translation).(2013) Vol I. New Delhi. CCRUM Ministry of Health and Family Welfare; Pp:284-286,342-344,500-503,626-629.
Khan Mohd Azam. Muheet e Azam (Urdu Translation).(2013) Vol II. New Delhi. CCRUM Ministry of Health and Family Welfare; Pp:801-802
Khan Mohd Azam. Muheet e Azam (Urdu Translation).(2013) Vol IV. New Delhi. CCRUM Ministry of Health and Family Welfare; Pp:82-84
Kirtikar KR, Basu BD. Indian Medicinal Plants. Vol II. 2nded. Dehradun. International Book Distributors; 1981:25,207-209,296-297,727-728.
Marthin JK, Petersen N, Skovgaard LT, Nielsen KG. Lung function in patients with primary ciliary dyskinesia: A cross-sectional and 3-decade longitudinal study. Am J Respir Crit Care Med. 2010; 181:1262-8. https://doi.org/10.1164/rccm.200811-1731oc
Mayank Mishra et al., Kartagener's syndrome: A case series; Lung India. 2012; 29(4):366-9. https://doi.org/10.4103/0970-2113.102831
McComb P, Langley L, Villalon M, Verdugo P. The oviductal cilia and Kartagener's syndrome. Fertil Steril. 1986; 46:412-6.
Olbrich H, Häffner K, Kispert A, Völkel A, Volz A, Sasmaz G et al., Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left-right asymmetry. Nat Genet. 2002; 30:143-4. https://doi.org/10.1038/ng817
Samuel I. Kartagener's syndrome with normal spermatozoa. JAMA. 1987; 258:1329-30.
Seiwert AK. Übereinen Fall von Bronchiekt-asiebeieinemPatientenmit situs inversus viscerum. Berlin Klin Wschr. 1904;41:139–141.
Shyama K and Prudence AR. Improving antibiotic prescribing pattern and assessment of co-morbidities associated with respiratory tract infections. Int J Pharm Pharm Sci 2017;9:283-6. https://doi.org/10.22159/ijpps.2017v9i2.15495
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