National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The investigation explores the characteristics of Bacopa monnieri, a renowned herb in Ayurvedic medicine referred to as 'Brahmi' for its wide-ranging applications in pharmacology, cosmetics, nutraceuticals, etc., showcasing efficacy against ulcers, inflammation, and asthma. The present study explores the antibacterial potential of B. monnieri for oral hygiene, particularly its impact on dental caries causing microorganisms, demonstrating favorable outcomes in both traditional and modern medical practices, offering cognitive enhancement and overall health benefits. The research aims to assess the antibacterial effectiveness against oral bacteria (Streptococcus mutans, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa) utilizing the agar cup/plate technique by testing six different concentrations of methanolic extract derived from Bacopa monnieri (L.) Pennell. The results indicate that Bacopa monnieri Methanolic extract (BmMe) exhibits significant antimicrobial activity against both Gram-positive and Gram-negative bacterial strains, with a concentration-dependent response observed in the zone of inhibition (ZOI) diameters, sup-ported by the presence of various bioactive compounds identified through phytochemical screening, suggesting its potential as a natural antimicrobial agent and encouraging further exploration for incorporating it into mouthwash formulations as an innovative oral hygiene practices.
Cruz, A. S. D. C., Fidelis, Y. P., De Mendonça Guimarães, D., Muller, H. S., Martins, V. D. P., Lia, E. N., 2022. Oral health and the presence of infectious microorganisms in hospitalized patients: a preliminary observational study. Annals of Medicine 54, 1908–1917. https://doi.org/10.1080/07853890.2022.2092895
Das, B. K., Al?Amin, M. M., Russel, S. M., Kabir, S., Bhattacherjee, R., Hannan, J. M. A., 2014. Phytochemical Screening and Evaluation of Analgesic Activity of Oroxylum indicum. Indian J Pharm Sci 76, 571–575.
Dubey, T. and Chinnathambi, S., 2019. Brahmi (Bacopa monnieri): An ayurvedic herb against the Alzheimer’s disease. Archives of Biochemistry and Biophysics 676, 108153. https://doi.org/10.1016/j.abb.2019.108153
Emran, T. B., Rahman, M. A., Uddin, M. M. N., Dash, R., Hossen, M. F., Mohiuddin, M., Alam, M. R., 2015. Molecular docking and inhibition studies on the interactions of Bacopa monnieri’s potent phytochemicals against pathogenic Staphylococcus aureus. DARU J Pharm Sci 23, 26. https://doi.org/10.1186/s40199-015-0106-9
Jeddy, N., Ravi, S., Radhika, T., Sai Lakshmi, L. J., 2018. Comparison of the efficacy of herbal mouth rinse with commercially available mouth rinses: A clinical trial. J Oral Maxillofac Pathol 22, 332–334.
https://doi.org/10.4103/jomfp.JOMFP_303_18
Kancherla, N., Dhakshinamoothi, A., Chitra, K., Komaram, R. B., 2019. Preliminary Analysis of Phytoconstituents and Evaluation of Anthelminthic Property of. MAEDICA – a Journal of Clinical Medicine 14, 350–356. https://doi.org/10.26574/maedica.2019.14.4.350
Khan, A. V., Ahmed, Q. U., Shukla, I., Khan, A. A., 2010. Antibacterial efficacy of Bacopa monnieri leaf extracts against pathogenic bacteria. Asian Biomedicine 4, 651–655. https://doi.org/10.2478/abm-2010-0084
Mandal, S., Mandal, M. D., Pal, N. K., 2007. Antibacterial potential of Azadirachta indica seed and Bacopa monniera leaf extracts against multidrug resistant Salmonella enterica serovar Typhi isolates. Arch Med Sci.
Mehta, J., Utkarsh, K., Fuloria, S., Singh, T., Sekar, M., Salaria, D., Rolta, R., Begum, M. Y., Gan, S. H., Rani, N. N. I. M., Chidambaram, K., Subramaniyan, V., Sathasivam, K. V., Lum, P. T., Uthirapathy, S., Fadare, O. A., Awofisayo, O., Fuloria, N. K., 2022. Antibacterial Potential of Bacopa monnieri (L.) Wettst. and Its Bioactive Molecules against Uropathogens—An In Silico Study to Identify Potential Lead Molecule(s) for the Development of New Drugs to Treat Urinary Tract Infections. Molecules 27, 4971. https://doi.org/10.3390/molecules27154971
Mkk, F., Sp, D., Irfan, M., 2019. Antibacterial and antifungal activity of various extracts of Bacopa monnieri. International Journal of Pharmaceutical Research 11, 1698–1702.
Rajashekharappa, S., Harish, P. D., Gowdar, B., 2008. Antibacterial Activity of Bacoside-A- an Active Constituent Isolated of Bacopa monnieri (L.) Wettest.
Shankar, P. S., Preeti, B., Santanu, B., Gajanan, D., Rupesh, D., 2018. Brahmi (Bacopa monnieri) as functional food ingredient in food processing industry. Journal of Pharmacognosy and Phytochemistry 7, 189–194.
Tamboli, F. A., Rangari, V. D., Tarlekar, S. D., Jadhav, R. D., Alaskar, K. M., Desai, V. V., Kanthe, R. U., 2022. Brahmi (Bacopa monnieri): an ayurvedic herb in the management of various diseases. Journal of Postharvest Technology 10, 59–74.
Teh, J. Y., Rawi, R., Noor, S. S. M., Taib, H., Mohamad, S., 2015. In-vitro antimicrobial effectiveness of herbal-based mouth rinses against oral microorganisms. Asian Pacific Journal of Tropical Biomedicine 5, 370–374. https://doi.org/10.1016/S2221-1691(15)30371-3
Theeba P, C. G. and Sasi Kumar, R., 2015. phytochemical-examination-antioxidant-potential-and-in-vitro-antibacterial studies-of-crude-extracts-of-parthenium-hyster.pdf. JOPCR 7, 219–225.
Verma, M., 2014. Ethnomedicinal and antimicrobial screening of Bacopa monnieri (L.) pennell. Journal of Phytology 6.
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