National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Gram-negative organisms are commonest cause of Urinary Tract Infection (UTI). Gram-positive bacteria from urine samples are often disregarded as contaminants. However, Gram-positive organisms are established uropathogens and their numbers are expanding. Materials and Methods: Urine samples received from January 2018 up-to December 2019 and January 2022 up-to December 2023 from suspected UTI cases of our institute were processed for culture and antibiotic susceptibility test. Gram-positive uropathogens isolated and their trend, demographic features and antibiotic susceptibility pattern were analyzed. Result: 28,365 urine samples were processed and 386 Gram-positive bacteria were isolated. Gram-positive uropathogens were 4%, 5%, 9% and 12% in 2018, 2019, 2022 and 2023 respectively. Enterococcus faecalis were 39%, Enterococcus faecium 25%, Streptococcus agalactiae 16%, Staphylococcus haemolyticus 7%, Methicillin Sensitive Staphylococcus Aureus 5%, Methicillin Resistant Staphylococcus Aureus 4%, Staphylococcus saprophyticus 2% and Staphylococcus epidermidis 2%. The importance of escalating number of Gram-positive bacteria as uropathogens especially in specific age groups and antibiotic susceptibility pattern is highlighted.
Bhargava K, Nath G, Bhargava A, Kumari R, Aseri G K and Jain N. Bacterial profile and antibiotic susceptibility pattern of uropathogens causing urinary tract infection in the eastern part of Northern India. Front. Microbiol. 2022; 13:965053. https://doi.org/10.3389/fmicb.2022.965053
Bushra, Anam, Mustafa M, Anjum I, Empiric therapy for community acquired urinary tract infection in an era of increasing antimicrobial resistance. IP Int J Med Microbiol Trop Dis 2023;9(4):267-274. https://doi.org/10.18231/j.ijmmtd.2023.050
Clinical Laboratory Standard International (CLSI) guidelines 2023.
Eipa R B, Islam R, Sultana R, Alam T S, Mehjabin T, Noon N et al., Determination of the antibiotic susceptibility pattern of Gram-positive bacteria causing UTI in Dhaka, Bangladesh. Biomedical and Biotechnology Research Journal 2023; https://doi.org/10.4103/bbrj.bbrj_159_23
Eltwisy H. O, Twisy H. O; Hafez M. H. R, Sayed I M, El-Mokhtar M. A. Clinical Infections, Antibiotic Resistance, and Pathogenesis of Staphylococcus haemolyticus. Microorganisms 2022; 10:1130. https://doi.org/10.3390/microorganisms10061130.
Fernández-Espigares, L.; Hernández-Chico, I.; Expósito-Ruiz, M.; Rosales-Castillo, A.; Navarro-Marí, J. M.; Gutiérrez-Fernández, J. Antibiotic Resistance Changes in Gram-Positive Bacteria from Urine Cultures: Development Analysis in a Health Area of South-East Spain. Antibiotics. 2023;12, 1133. https://doi.org/10.3390/antibiotics12071133
Forbes Betty A, Sahm Daniel F, Weissfield Alice S. Bailey and Scott’s Diagnostic Microbiology.12th ed. St Louis, Missouri 63146: Mosby Elsevier 2007:842-855.
Kline A K and Lewis A M. Gram-Positive Uropathogens, Polymicrobial Urinary Tract Infection, and the Emerging Microbiota of the Urinary Tract. Microbiol Spectr. 2016; 4(2): https://doi.org/10.1128/microbiolspec.UTI-0012-2012.
Laila U U, Jahan N, Nahar S, Rana M, Sultana F, et al., Gram-positive uropathogens: Empirical treatment and emerging antimicrobial resistance. Biomed Res Clin Prac 4. 2019: https://doi.org/10.15761/BRCP.1000182
Smout E, Palanisamy N, Valappil P S. Prevalence of vancomycin-resistant Enterococci in India between 2000 and 2022: a systematic review and meta-analysis. Antimicrobial Resistance & Infection Control 2023; 12:79. https://doi.org/10.1186/s13756-023-01287-z.
Verma S B, Rachna, Sharma A. Prevalence of Gram-positive cocci in urinary tract infection patients and their antimicrobial susceptibility pattern at tertiary care hospital in North India. International Journal of Scientific Research 2020;9(5):44-46. https://doi.org/10.36106/ijsr
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