Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(3): 502-512
DOI: http://dx.doi.org/10.20546/ijcmas.2016.503.059


Role of Acinetobacter as pathogen of Health care Associated Pneumonia and Blood Stream Infections in ICU Setting in a Tertiary Care Hospital in New Delhi
Ruchi  Girotra*, Raman Sardana, Reetika Dawar, Leena Mehndiratta, Sudha Kansal, Rajesh Chawla Ruby Naz and Narendra Agarwal
Department of Microbiology, Indraprastha Apollo Hospitals, New Delhi, India
*Corresponding author
Abstract:

Invasive diseases due to Acinetobacter is an increasing problem in health care settings and especially in Intensive Care Units (ICU) worldwide. These organisms occur as components of commensal flora of man and animals and are therefore regular contaminants of hospital environment. Purpose-This prospective study was conducted at Indraprastha Apollo Hospitals, New Delhi in the Department of Microbiology and Respiratory and Critical Care Medicine to ascertain the role of Acinetobacter as a Pathogen in Healthcare Associated Pneumonia (HCAP) and Blood stream Infections(BSI). Findings-One hundred and eight consecutive, non repeat isolates of Acinetobacter species isolated from blood and respiratory tract were studied. Nineteen cases were identified together as Healthcare associated pneumonia (HCAP) and blood stream infections(BSI). By applying Fishers Exact Test,the colonization rate vs the infection due to Acinetobacter species rate was calculated to be 82.41% (BSI+HCAP) and 17.59% which was found to be significantly in in favour of colonization.(p- value0.001). Tracheostomy was a significant risk factor associated with the development of HCAP due to Acinetobacter species (p-value< 0.05)(Fishers Exact Test) while Immunosuppression (p-value≤0.05.) and presence of multiple catheters(p<0.05) were independent risk factors in BSI infections. Immunosuppression was found to be significantly higher in the BSI group compared to the Non-BSI group. Conclusion- This study shows that mere colonisation by Acinetobacter species should not be considered as an indication for antimicrobial treatment for the same as a very small proportion of Acinetobacter species was responsible for infection.


Keywords: Acinetobacter, Healthcare Associated Pneumonia, blood stream infections,risk factors, Intensive Care Units
Download this article as Download

How to cite this article:

Ruchi  Girotra, Raman Sardana, Reetika Dawar, Leena Mehndiratta, Sudha Kansal, Rajesh Chawla Ruby Naz and Narendra Agarwal. 2016. Role of Acinetobacter as pathogen of Health care Associated Pneumonia and Blood Stream Infections in ICU Setting in a Tertiary Care Hospital in New DelhiInt.J.Curr.Microbiol.App.Sci. 5(3): 502-512. doi: http://dx.doi.org/10.20546/ijcmas.2016.503.059