National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Fever could have many causes including infective and non infective origin. PUO is a clinical syndrome that may result from much common aetiology which was characterized by prolonged fever without the signs or symptoms indicative of a well defined disease process. The aim of the study to find the infectious causes of fever by microscopy, serology and culture methods, to compare quantitative buffy coat vs peripheral smear study for the detection of malarial parasite and to find out Antimicrobial Susceptibility pattern of the organisms isolated. Among the 125 patients selected 66 were males and 59were females. The causes of Pyrexia of unknown origin were Infectious in 62.4%, Collagen disorder in 3.2%, Neoplasm in 2.4%, Miscellaneous in 6.4% and undiagnosed in 25.6% of patients. In Infectious causes chronic urinary tract infection was the commonest cause (12.8%) followed by malarial fever (11.2%), Leptospirosis (10.4%), enteric fever (8.0%), hepatitis (6.4%), tuberculosis (5.6%) and less frequently acquired immuno deficiency syndrome (1.6%), pancreatitis (1.6%), viral meningitis (1.6%), Rheumatic fever (0.8%), filariasis (0.8%), sinusitis (0.8%) and liver abscess (0.8%) were documented the source of PUO in the selected group. In 62.4% of cases with fever more than 3 weeks were caused by infectious origin. Causes were unknown in 25.6% of patients.UTI was the most common cause in infectious origin.QBC is more sensitive to detect malarial parasite than Peripheral smear study. The sensitivity of Detection in Leptospiral aetiology by MSAT were high compared with IgM ELISA. Brucellosis, granulomatous diseases and certain neoplastic disorders would have contributed to the undiagnosed group in the diagnosis of PUO.
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