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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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Original Research Articles                      Volume : 12, Issue:5, May, 2023

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2023.12(5): 45-50
DOI: https://doi.org/10.20546/ijcmas.2023.1205.006


Study of Antibiotic Resistance Pattern in Methicillin-Resistant Staphylococcus aureus with Special Reference to Newer Antibiotics in a Tertiary Care Hospital in Haryana, India
Komal*, Aparna Yadav, Antarikshdeep, Madhu Sharma and Jugal Kishor
Department of Microbiology, Pt. B.D. Sharma PGIMS, Rohtak-124001, Haryana, India
*Corresponding author
Abstract:

Background: Staphylococcus aureus (S. aureus) is a leading source of nosocomial infections, such as ventilator-associated pneumonia, surgical site infections and bloodstream infections. Materials and method: This study was conducted in the Department of Microbiology Pt. B.D. Sharma University of Health Sciences, Rohtak on 200 isolates of S. aureus. Results: The rate of isolation of S. aureus was maximum from pus (77.0%) followed by blood (23%). The prevalence of Methicillin-resistant Staphylococcus aureus (MRSA) was observed in 55% of S. aureus isolates. MRSA was significantly more among Pus samples. As per D-Zone test, inducible clindamycin resistance was found among 20 (18.2%) isolates. As per vancomycin E-test, vancomycin was found to be sensitive in 106 (96.4%) and intermediate sensitive in 4 (3.6%) isolates. Linezolid and daptomycin were found to be sensitive in all (100.0%) isolates. Conclusion: We concluded that S. aureus is a pervasive pathogen in both our hospital and in community settings, with constantly changing trends in virulence, resistance and epidemiology.


Keywords: Antibiotic, Methicillin resistant Staphylococcus aureus, Infection, Pus, Blood

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How to cite this article:

Komal, Aparna Yadav, Antarikshdeep, Madhu Sharma and Jugal Kishor. 2023. Study of Antibiotic Resistance Pattern in Methicillin-Resistant Staphylococcus aureus with Special Reference to Newer Antibiotics in A Tertiary Care Hospital in Haryana.Int.J.Curr.Microbiol.App.Sci. 12(5): 45-50. doi: https://doi.org/10.20546/ijcmas.2023.1205.006
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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