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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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Original Research Articles                      Volume : 11, Issue:12, December, 2022

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2022.11(12): 146-150
DOI: https://doi.org/10.20546/ijcmas.2022.1112.014


Effect of on 1,2,3-Triazole Derivatives the Activity of Liver Antioxidant Enzymes in Alloxan Diabetes
Muydinov Izzatulla Ismatillayevich1, OrtikovI lkhomjon Sobirovich2,
Makhsudova Makhliyokhon Fakhriddin qizi3 and Pozilov Mamurjon Komiljonovich4
1Doctoral student of Andijan State University, 2Doctoral student of Institute of the Chemistry of Plant Substances of AS RUz, 3Student of the National University of Uzbekistan,
4Department of Biophysics of the, National University of Uzbekistan named after Mirzo Ulugbek, Uzbekistan
*Corresponding author
Abstract:

In this study, the effects of 1,2,3-triazo derivatives on the amount of lipid peroxidation product malondialdehyde (MDA) and superoxide dismutase (SOD), catalase activity in rat liver homogenate under the conditions of alloxan diabetes were studied.New derivatives of triazoles, TF-25, TS-27 and TB-31, were found to inhibit MDA content in rat liver homogenate and increase activity of antioxidant enzymes SOD and catalase in alloxan diabetes.


Keywords: Liver, antioxidant, MDA

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How to cite this article:

Muydinov Izzatulla Ismatillayevich, OrtikovI lkhomjon Sobirovich, Makhsudova Makhliyokhon Fakhriddin qizi and Pozilov Mamurjon Komiljonovich. 2022. Effect of on 1,2,3-Triazole Derivatives the Activity of Liver Antioxidant Enzymes in Alloxan Diabetes.Int.J.Curr.Microbiol.App.Sci. 11(12): 146-150. doi: https://doi.org/10.20546/ijcmas.2022.1112.014
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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