International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 10, Issue:10, October, 2021

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2021.10(10): 651-656

Microbial Profile and Antimicrobial Susceptibility pattern of Organisms isolated in Neonatal Sepsis in Tertiary care Hospital
S. Deepa1, B. Padmini2*, S. Rajesh3 and P. Mythili3
1Department of Microbiology, Govt. Mohan Kumaramangalam Medical College,Salem, Tamilnadu, India 2Department of Microbiology, Coimbatore Medical College, Coimbatore, Tamilnadu, India 3Department of Microbiology, Karur Medical College, Karur, Tamilnadu, India
*Corresponding author

Neonatal Sepsis is one of the leading causes of neonatal morbidity and mortality worldwide. Frequent monitoring on causative pathogens and their antimicrobial susceptibility pattern is mandatory for the better treatment. The present study was undertaken to identify the common bacterial pathogens causing Neonatal sepsis and their antimicrobial susceptibility pattern at Neonatal Intensive Care Unit (NICU). Blood cultures were performed for 400 clinically suspected cases of neonatal septicaemia and 36% (144 cases) were culture positive. Of these, 61% cases were early onset septicemia (EOS) and 39% were late onset septicemia (LOS). Among culture positive cases, the bacteriological profile was found highest for Klebsiella pneumoniae (59.7%) followed by Acinetobater species (16.6%) among Gram negative isolates and CoNS(4%) was the predominant Gram-positive pathogen. Imipenem showed highest 100% sensitivity and Cefotaxime least (30 %) sensitivity to Gram-negative isolates. This concludes that broad range of bacteria are associated with neonatal sepsis and revealed variation in antimicrobial susceptibility pattern among bacterial isolates.

Keywords: Neonatal septicaemia, Antimicrobial susceptibility, Bacteriological profile

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How to cite this article:

Deepa, S., B. Padmini, S. Rajesh and Mythili, P. 2021. Microbial Profile and Antimicrobial Susceptibility pattern of Organisms isolated in Neonatal Sepsis in Tertiary care Hospital.Int.J.Curr.Microbiol.App.Sci. 10(10): 651-656. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.