International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 11, Issue:9, September, 2022

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2022.11(9): 131-135

Effect of Carbon tetrachloride on Liver enzymes and Lipid Peroxidation in Rat
Neogy Ganguli, Rabindra Nath Hansda*, S. Mondal, S. Pradhan and S. K. Mukhopadhyay
Department of Veterinary Pathology, Faculty of Veterinary and Animal Sciences, West Bengal University of Animal and Fishery Sciences, Kolkata-700037, India
*Corresponding author

In this present study, 12(twelve) albino rats divided into two groups. Each group consisting of three males and three females. T1 for control group received only liquid paraffin @ 3ml/kg.b.wt. on alternate day for four injections. T2 group treated with carbon tetrachloride @ 1ml/kg.b.wt. following dilution with liquid paraffin at the ratio of 1: 2 i.e. 3ml/kg.b.wt. subcutaneously on alternate day for four injections. T2 group rats showed decreased reduced glutathione(5%), increased lipid peroxidation(60%) and decreased SGOT(62.4%). The pathological changes in the liver tissue showed fally changes, coagulative necrosis, cirrhosis and hyperplasia of bile duct.

Keywords: Carbon tetrachloride,albino rat, liver, xenobiotics

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How to cite this article:

Neogy Ganguli, M., Rabindra Nath Hansda, S. Mondal, S. Pradhan and Mukhopadhyay, S. K. 2022. Effect of Carbon tetrachloride on Liver enzymes and Lipid Peroxidation in Rat.Int.J.Curr.Microbiol.App.Sci. 11(9): 131-135. doi:
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