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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(2): 1908-1911
DOI: http://dx.doi.org/10.20546/ijcmas.2017.602.216


Comparative Study on Biochemical Markers: Patients Infected By Dengue Virus
R. Aruna1 and M. Prakash2*
1Research and Development Centre, Bharathiar University, Coimbatore-641 046, Tamil Nadu, India
2Department of Microbiology, Kanchi Shri Krishna College of Arts and Science, Kilambi, Kancheepuram-631 551, Tamil Nadu, India
*Corresponding author
Abstract:

Dengue is a vector borne viral infection that belongs to family Flaviviridae. It is a single stranded RNA virus and endagers 2.5 billion people worldwide. WHO has estimated about 50 million cases of dengue infection every year worldwide. Apoptotic hepatocytes are found to be colocalised with dengue virus infected hepatocytes, suggesting that hepatocytes are the major site of dengue virus replication in the liver. Therefore, the aim of the present study is to analyse the role of liver enzymes in Dengue viral infection. The present study was carried out in Indira Gandhi Government General Hospital & Post graduate Institute, Puducherry. 486 dengue positive patients were chosen from the hospital from the period of September 2014 to January 2015. The samples were processed for SGOT and SGPT by UV enzymatic kinetic method (Linear chemicals . S.L.) as per manufacturer’s instructions. The values were recorded by spectro photometry. The NS1Ag samples were found to be increased SGOT and SGPT values than IgM affected patients. No IgG reactive patient was found to have increased SGOT levels.


Keywords: Dengue patients, SGOT, SGPT, liver damage, Management
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How to cite this article:

Aruna, R., and Prakash, M. 2017. Comparative Study on Biochemical Markers: Patients Infected By Dengue Virus.Int.J.Curr.Microbiol.App.Sci. 6(2): 1908-1911. doi: http://dx.doi.org/10.20546/ijcmas.2017.602.216