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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2021.10(6): 606-612
DOI: https://doi.org/10.20546/ijcmas.2021.1006.066


Methicillin Resistance and Biofilm Formation of Clinically Important Coagulase Negative Staphylococci
Subitha1* and J. Pavithra Devi2
1Department of Microbiology, Govt. Thoothukudi Medical College,
Thoothukudi - 628008, Tamil Nadu, India
2Department of Microbiology, Govt. Stanley Medical College,
Chennai – 600001, Tamil Nadu, India
*Corresponding author
Abstract:

Nowadays Coagulase-negative staphylococci (CoNS) are the most common causes of device related infections, especially in extreme age group of patients such as neonates and old age. The antibiotic resistance and biofilm production of CoNS produce negative impact on clinical outcome of patients, The study is therefore conducted to determine the antimicrobial susceptibility pattern and surface adherence property of CoNS isolated from various clinical specimens.. During the six months study period 46 CoNS were isolated from various clinical specimens Staphylococcus epidermidis (47%) was the common isolate followed by Staphylococcus haemolyticus (24%), and Staphylococcus saprophyticus (24%). CoNS isolates showed maximum resistance to Ampicillin (76%), Clindamycin(74%), Cotrimoxazole (74%) and Erythromycin(72%). CoNS isolates revealed 100% sensitivity to Vancomycin. 72% of CoNS isolates showed Methicillin resistance and 61% were biofilm producers by Congo Red Agar method. Methicillin resistance and Biofilm production of CoNS lead to increased morbidity and mortality in hospitalized patients. Aseptic management should be followed in intravascular devise insertion and other invasive procedures to reduce the spread of CoNS infection.


Keywords: CoNS, Methicillin resistance, Biofilm production
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How to cite this article:

Subitha, B. and Pavithra Devi, J. 2021. Methicillin Resistance and Biofilm Formation of Clinically Important Coagulase Negative Staphylococci.Int.J.Curr.Microbiol.App.Sci. 10(6): 606-612. doi: https://doi.org/10.20546/ijcmas.2021.1006.066