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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2021.10(6): 29-39
DOI: https://doi.org/10.20546/ijcmas.2021.1006.003


Comparative Histomorphological Changes of Bovine Foot and Mouth Disease (FMD) at different Clinical Stages in Bangladesh
Department of Anatomy and Histology, Bangladesh Agricultural University,  Mymensingh-2202, Bangladesh
Department of Anatomy and Histology, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh
*Corresponding author
Abstract:

The aim of this study was to determine the comparative histomorphological changes of bovine Foot and Mouth Disease (FMD) at different clinical stages in clinically some infected and non-infected diseased cattle. The disease was characterized by fever and vesicular eruption in the mouth, nares, muzzle, foot, teats and other hairless soft areas of the body and morphologically moderate raised values (p≤0.05) were recorded in rectal temperature, respiratory and pulse rate, where highest values were during 3 to 7 days of post infection which subsequently reduced after passing the days of infection. Microscopic changes were observed at the advanced stages in the tongue epithelium of the infected cattle, which consisted of ballooned epithelial cells of stratum spinosum showing eosinophilic cytoplasm, acantholysis, pyknotic nucleus with granulocyte infiltration and complete necrosis or dissolution of stratified squamous epithelial surface and the filiform papillae rather than the control, primary and recovery stages. These changes were progressed to microvesicle which on coalescence formed grossly visible macrovesicle (bullae). While, loss of striation of the intercalated bundles of striped muscles fibers and necrosis with intense neutrophil infiltration in the interdigital (foot) space epithelium were observed only at the recovery stages. Therefore the comparative relationship of elevated body temperature, respiratory, pulse rate with histological changes at different clinical stages in this research might be helpful for the virologists, cell-biologists, anatomists and veterinarians to plan for the better management, prevention and future control strategies of FMD.


Keywords: Histomorphology, FMD, Vesicles, Cattle, Days of post infection
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How to cite this article:

Md. Ashraf Zaman Faruk and Shonkor Kumar Das. 2021. Comparative Histomorphological Changes of Bovine Foot and Mouth Disease (FMD) at different Clinical Stages in Bangladesh.Int.J.Curr.Microbiol.App.Sci. 10(6): 29-39. doi: https://doi.org/10.20546/ijcmas.2021.1006.003