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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2021.10(5): 826-834
DOI: https://doi.org/10.20546/ijcmas.2021.1005.092


Microbiological Profile of Chronic Osteomyelitis in a Tertiary Care Hospital
B. Padmini1 and S. Deepa2*
1Department of Microbiology, Coimbatore Medical College, Coimbatore, Tamil Nadu, India 2Department of Microbiology, Govt. Mohan Kumaramangalam Medical College, Salem, Tamil Nadu, India
*Corresponding author
Abstract:

Osteomyelitis is the infection and inflammation of the bone. Inappropriate use of antibiotics and multidrug resistance has raised the morbidity and mortality rate in chronic osteomyelitis. This study aims to determine the bacterial profile and antimicrobial susceptibility patterns of chronic osteomyelitis with special mention to various resistant mechanisms. Samples from osteomyelitis cases were aerobically cultured and isolates from culture positives were identified by standard procedures. Antimicrobial susceptibility testing was done by Kirby Bauer disk diffusion method. Staphylococcal isolates were screened for methicillin resistance. The aerobic bacteriological study of chronic osteomyelitis showed Staphylococcus aureus is being continued to be major etiological agent followed by Pseudomonas aeruginosa and CoNS. Gram-positive isolates were sensitive to linezolid, Vancomycin while gram-negative isolates were sensitive to Meropenem and Pipericillin with Tazobactum in the majority. In present study prevalence of methicillin-resistant Staphylococci aureus was found to be on the higher side. Antibiotic therapy on the basis of antibiotic susceptibility pattern helps the clinician to choose appropriate drugs leading to successful treatment and prevention of emergence and dissemination of drug resistant isolates.


Keywords: Poor blood supply, diabetic wounds, loss of protective sensation and altered immune defenses
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How to cite this article:

Padmini, B. and Deepa, S. 2021. Microbiological Profile of Chronic Osteomyelitis in A Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 10(5): 826-834. doi: https://doi.org/10.20546/ijcmas.2021.1005.092