National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Acinetobacter can survive for a long time in hospital environments, and colonizes almost all patients on prolonged hospitalization. Additionally, they are often multi-drug resistant. The present study aims at assessing the incidence and susceptibility pattern of Acinetobacter species in a tertiary care center. Retrospective study analyzing1169clinical isolates identified as Acinetobacter using Gram’s-stained smears, colony characteristics and biochemical reactions. Antibiotic Susceptibility Testing was performed by Kirby - Bauer Disc Diffusion Method, using antibiotics as per latest CLSI guidelines. Most isolates occurred in pus and wound swabs (506), followed by tracheal aspirates and sputum (271) and Bacteremia (249). Additionally, 56.48% isolates of Acinetobacter were from patients admitted for over two weeks; these findings were statistically significant These were generally resistant to Cephalosporins (24.70% Sensitive), and relatively susceptible to β-Lactam + β- Lactamase Inhibitor combinations (41.47& Sensitive), and generally susceptible to Tetracyclines (55.87% Sensitive). The present study confirms the multi-drug resistant nature of Acinetobacter species, and highlights the correlation between its incidence and duration of hospitalization. Rigorous use of standard precautions and minimizing hospital stay would reduce infection, and consequently, antibiotic overuse, which contributes further to drug resistance. In addition, a robust antibiotic policy and antibiotic stewardship in the hospital can minimize its incidence.
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