International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 10, Issue:3, March, 2021

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2021.10(3): 100-107

Seropositivity of ToRCH infection in Pregnant Women in Tertiary Care Hospital
Vishakha Asopa1, Eshank Gupta1, Anita Kumari Gupta1,S. Dalal2 and Prabhu Prakash1*
Department of Microbiology, Dr SNMC, Jodhpur, India
Department of Microbiology, GMCH, Udaipur, India
*Corresponding author

ToRCH is an acronym which stands for Toxoplasma gondii, Rubella virus, Cytomegalovirus (CMV), Herpes simplex virus-II (HSV-II) and other agents like Zika virus, HIV, Treponema pallidum, Niesseria gonorrhoeae, etc are the major cause of bad obstetric history (BOH). These pathogens usually cause only asymptomatic or mild infections in mother, but can cause much more serious consequences in fetus. The present study was aimed to find seroprevalence in pregnant population to explore the burden of ToRCH [toxoplasma, rubella virus, cytomegalovirus (CMV) and herpes simplex virus (HSV)] infection in southern Rajasthan. This was a prospective study conducted in a tertiary care center, Udaipur .The study period was carried over one year. Total 111 non duplicate blood samples were collected from pregnant women. Seropositivity (IgM/IgG) of ToRCH infection in pregnant women were detected by Chemiluminescence Immuno assay method. Herpes simplex virus -2 was detected by Enzyme linked immunosorbent assay. Out of 111 screened pregnant women, overall seropositivity (IgM/IgG) for Toxoplama gondii was 03 (2.70%), Rubella 43 (38.74%), Cytomegalovirus 52(46.85%) and Herpes simplex –II was 02(1.80%). Seropositivity of IgM for specific ToRCH agents were as follows: Toxoplama 02(1.80%), Rubella was 15(13.51%), Cytomegalovirus was 20(18.01%) and Herpes simplex –II was 01 (0.90%). The higher seropositivity (IgM/IgG) was found between 20 to 40 years. Higher seropositivity rates were observed in pregnant women who were in first trimester. It is recommended that all pregnant women with BOH should be routinely screened for ToRCH agents at the first antenatal visit as ToRCH infections play a major role in adverse fetal outcome. Awareness amongst clinicians and patients about ToRCH infections and their consequences should developed.

Keywords: ToRCH, Bad obstetric history, IgG, IgM, Antenatal clinic

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How to cite this article:

Vishakha Asopa, Eshank Gupta, Anita Kumari Gupta, A. S. Dalal and Prabhu Prakash. 2021. Seropositivity of ToRCH infection in Pregnant Women in Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 10(3): 100-107. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.