Milk obtained from the udder of a healthy milch animal is almost in sterile condition but gets contaminated during milking, transportation, storage and processing and also due to the entry of microbes through many other sources. Insufficient sanitization and cleaning causes contaminants to accumulate in milk processing equipment which subsequently form biofilm that further become significant source of contamination of dairy products. Biofilm is aggregations of microbial cells interconnected by extracellular polymeric substances which accelerate growth on different material surfaces adversely affect the dairy industry. Biofilm formation possesses profound implications and throws a major challenge to the dairy sector where they act as the principal reservoir of microbial contamination. These lead to financial crisis by impairment of raw material and its products. It is emphasized that god manufacturing practice, good hygienic practice and hazard analysis and critical control point should be implement in dairy industry to prevent the contamination of dairy products.

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