National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Helicobacter pylori is a global pathogen, ultimately affecting fifty percent of the population of the world. It has developed resistance to routinely used antibiotics. Subsequently, it is imperative to locate an alternative treatment for Helicobacter pylori. Xembran®, a combination of Myristica fragrans and pure Shankha Bhasma was tested for its anti-Helicobacter pylori activity. The activity of Xembran was determined by disc diffusion and the minimum bactericidal concentration method. The complete inhibition of Helicobacter pylori was achieved at a concentration of 70mcg by the disc diffusion method. Xembran was able to show greater activity against Helicobacter pylori with an increase in contact time. However, 0.5% concentration was adequate to execute the bactericidal effect on Helicobacter pylori with a contact time of 20 minutes. Xembran can serve as an alternative to routinely used antibiotics. Thus, it is a potential agent to combat Helicobacter pylori.
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