National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Adverse drug reactions are described as “A response to a medicine in a human which is noxious and unintended and which occur at any dosage and can also result from an overdose, misuse or abuse of a medicine. Adverse cutaneous drug reactions (ACDRs) are caused by a wide variety of drugs. Aim of the study is to determine the clinical patterns of drug eruptions and the common drugs implicated and determine the frequency of incriminating drugs for different patterns of CADRs. The time duration of our study was about 6 months from January 2018 to December 2018 and 500 patients attending the dermatology OPD and IPD of MDM hospital were included in this study. All patients were examined clinically and history and informed consent were taken. All routine and any special investigations if needed were done and pro forma filled. The most common drug rectoins pattern was fixed drug eruptions in 220 (44%) patients followed by maculopapular rash in 115 (23%) patients, urticaria in 45 (9%), urticarial vasculitis in 15 (3%) and SJS in 30 (6%) patients. TEN and EM like in 25 (5%), LDR, Erythroderma, PR like, acneiform eruption and DRESS in 5 (1%) patients. The clinical patterns and causative drugs of cutaneous adverse drug reactions (CADR) are highly variable among the population. Thus a thorough knowledge of these drug eruptions and the causative drugs will help the clinician in minimizing the ACDRs and also in its timely management.
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