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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(6): 2733-2742
DOI: https://doi.org/10.20546/ijcmas.2020.906.332


Study of Clinico-Epidemiological Correlation and Clinical Pattern of Cutaneous Drug Reaction in Tertiary Level Hospital in Western Rajasthan
Virendra Kumar*, Vinod Jain, Dilip Kacchawaha, Pankaj Rao and C.P. Chouhan
Department of Skin & V.D, Dr. S.N. Medical College, Jodhpur, Rajasthan, India
*Corresponding author
Abstract:

Adverse drug reactions are described as “A response to a medicine in a human which is noxious and unintended and which occur at any dosage and can also result from an overdose, misuse or abuse of a medicine. Adverse cutaneous drug reactions (ACDRs) are caused by a wide variety of drugs. Aim of the study is to determine the clinical patterns of drug eruptions and the common drugs implicated and determine the frequency of incriminating drugs for different patterns of CADRs. The time duration of our study was about 6 months from January 2018 to December 2018 and 500 patients attending the dermatology OPD and IPD of MDM hospital were included in this study. All patients were examined clinically and history and informed consent were taken. All routine and any special investigations if needed were done and pro forma filled. The most common drug rectoins pattern was fixed drug eruptions in 220 (44%) patients followed by maculopapular rash in 115 (23%) patients, urticaria in 45 (9%), urticarial vasculitis in 15 (3%) and SJS in 30 (6%) patients. TEN and EM like in 25 (5%), LDR, Erythroderma, PR like, acneiform eruption and DRESS in 5 (1%) patients. The clinical patterns and causative drugs of cutaneous adverse drug reactions (CADR) are highly variable among the population. Thus a thorough knowledge of these drug eruptions and the causative drugs will help the clinician in minimizing the ACDRs and also in its timely management.


Keywords: Adverse cutaneous drug reaction, Maculopapular rash, Toxic epidermal necrolysis, LDR, DRESS
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How to cite this article:

Virendra Kumar, Vinod Jain, Dilip Kacchawaha, Pankaj Rao and Chouhan, C.P. 2020. Study of Clinico-Epidemiological Correlation and Clinical Pattern of Cutaneous Drug Reaction in Tertiary Level Hospital in Western Rajasthan.Int.J.Curr.Microbiol.App.Sci. 9(6): 2733-2742. doi: https://doi.org/10.20546/ijcmas.2020.906.332