International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2022 - IJCMAS--ICV 2022: 95.28 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020] For more details click here

Login as a Reviewer

See Guidelines to Authors
Current Issues
Download Publication Certificate

Original Research Articles                      Volume : 9, Issue:6, June, 2020

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(6): 759-764

Effect of Certain Immunomodulators on Subclinical Endometritis in Cattle
H.S. Sahoo, A.K. Barik, D.N. Mohanty*, P.C. Mishra, A.K. Nahak and B. Jena
H.S. Sahoo, A.K. Barik, D.N. Mohanty*, P.C. Mishra, A.K. Nahak and B. Jena
*Corresponding author

Forty sub-clinical endometritic (repeat breeding) cows were assigned to four groups, ten in each. Experimental design envisaged administration of Levamisole S/C, three injections at weekly interval @ 1ml/30kg body weight (group I), Restobal, a herbal drug 50 ml twice daily per animal orally for 10 days (group II), PHA-M @ 0.5 mg per cow through I/U once on the day of estrus (group III) and control (group IV) with no treatment. All the experimental cows were inseminated in the following estrus. Blood and uterine samples from each experimental animal were collected for evaluation of hematological parameters like haemoglobin concentration, total leucocyte count (TLC), differential count (DC) and uterine bacterial load during pre and post treatment period, consequent to various therapies as per standard procedures. The haemoglobin concentration (gm/dl), TLC values in different experimental groups did not reveal any significant difference at pre and post treatment period either within or between groups. In all the experimental groups the post treatment uterine bacterial count significantly receded (p<0.01) compared to their pre treatment values and also differed significantly (p<0.01) within and between the groups. The overall conception rate was highest (70 per cent) in group III subjected to therapy of PHA-M followed by 60%, 50% and 30% in Levamisole (group I), Restobal (group II) and control (group IV), respectively. Clinical management of sub-clinical endometritis (repeat breeding) by immunomodulating agents like PHA-M has got clinical importance.

Keywords: Endometritis, Immunomodulators

Download this article as Download

How to cite this article:

Sahoo, H.S., A.K. Barik, D.N. Mohanty, P.C. Mishra, A.K. Nahak and Jena, B. 2020. Effect of Certain Immunomodulators on Subclinical Endometritis in Cattle.Int.J.Curr.Microbiol.App.Sci. 9(6): 759-764. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.