National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Seaweeds are rich sources of natural bioactive products. Their interesting biological activities contributed to the investigation of natural therapeutic compounds used in biomedical and pharmaceutical applications. In this study, methanolic extracts of four seaweeds collected from the Moroccan Atlantic coastline (Agadir) Bifurcaria bifurcata, Corallina elongata, Corallina officinalis and Ulva fasciata were investigated for antimicrobial activities using the disc diffusion and broth microdilution methods. The extract bioactivity was expressed as minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against four human pathogenic bacteria Staphylococcus aureus, Escherichia coli, Bacillus subtilis and Pseudomonas aeruginosa. The results indicated that among the algal samples screened, the methanolic extract of B. bifurcata and U. fasciata exhibited the highest potency against all pathogens tested, with MIC ranged from 0.11 to 3.75 mg/ml depending on the bacterial species. The lowest MIC and MBC values were recorded for methanolic extract of B. bifurcata against Bacillus subtilis (0.11 mg/ml, 7.50 mg/ml) and E. coli (0.23 mg/ml, 7.50 mg/ml). Therefore, the present findings suggest that local seaweeds, chiefly B. bifurcata may be considered as an interesting biological source of bioactive compounds and should be investigated for natural antibiotics to control some pathogenic bacteria strains such as E. coli and B. subtilis.
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