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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(5): 2372-2385
DOI: https://doi.org/10.20546/ijcmas.2020.905.270


A Review on a Bio-Synthetic Pathway: Melanogenesis
Triparna Pahari1, Kasturi Chattopadhyay2, Susmita Mukherjee3* and Susmita Jana4
1Department of Fish Genetics and Breeding
2Department of Post-Harvest Technology ICAR- Central Institute of Fisheries Education (CIFE), Mumbai-400 061, India
3Department of Fish Processing Technology
4Department of Fisheries Resource Management West Bengal University of Animal and Fisheries Science, Kolkata- 700 094, India
*Corresponding author
Abstract:

Melanogenesis is a complex process that involves many genes which leads to production and distribution of the melanin pigment. Melanin is a dark biological pigment derived by the oxidation and subsequent polymerization of phenolic compounds. There are two types of melanin viz., eumelanin (black-brown color) and pheomelanin (yellow-red color). Melanin is found in different parts of the body of the animal like skin, brain, eye, ear and perform different functions apart from pigmentation. The main biosynthetic pathway of melanogenesis in all animals is Raper-Mason pathway. Melanogenesis pathway is regulated by different pathways which involve many genes like MC1R, AC, β-catenin, RAS, BRAF, MAPK, MITF etc. Melanin has very unique properties like redox capacity, metal chelating properties or free radical scavenging properties etc. Because of these properties Melanin and melanin like materials (PDA-polydopamine) have different applications in the field of dermatology, cosmetics, biomedicine as well as anti-pollution product technologies and many more. This review presents a general overview of melanin and melanogenesis in different types of organisms and applications of melanin in different biological fields.


Keywords: Melanogenesis, Eumelanin, Pheomelanin, Polydopamine, Biological application
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How to cite this article:

Triparna Pahari, Kasturi Chattopadhyay, Susmita Mukherjee and Susmita Jana. 2020. A Review on a Bio-Synthetic Pathway: Melanogenesis.Int.J.Curr.Microbiol.App.Sci. 9(5): 2372-2385. doi: https://doi.org/10.20546/ijcmas.2020.905.270