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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(2): 1076-1088
DOI: https://doi.org/10.20546/ijcmas.2020.902.126


Correlation of Biomarker and Biophysical Parameters with Microflora at Different Skin Sites in Young Women (20-21yrs.) of Meerut
Sonia Sharma1*, Alka Sagar1, Saurabh Singh Yadav2, Pramod W. Ramteke3
1Meerut Institute of Engineering and Technology, Meerut, India
2Swami Vivekanand Subharti University, Meerut, India
3Sam Higginbottom University of Agriculture Technology and Sciences, Allahabad, India
*Corresponding author
Abstract:

Dermal health is the outcome of dynamic interactions between the microflora and immune networks to influence the health and overall wellbeing. Biophysical parameters reflect the functional integrity of skin. Biomarkers LL-37 and HBD 2, 3 have broad spectrum amino acid activity that plays role in epithelial defense system.The aim of the present work was to find out exiting correlation between the isolated genera, biophysical parameters and biomarkers of skin. Methods of isolated genera from seven cutaneous site from 45 young girls (21-22 yrs.) were ccorrelated with Biophysical parameters such as trans-epidermal water loss, epidermal hydration, skin pH, dermal health, level of biomarkers LL-37 and HBD, Meerut Institute of Engineering and Technology (MIET), Meerut. One hundred six (136) isolates presumptively identified as Staphylococcus epidermidis, Pseudomonas sp., Lactobacillus sp. Propionobacterium sp. on the basis of selective media and biochemical characterization were analyzed. Total viable count was moderately correlated with LL-37, HBD-2,3, epidermal hydration and skin gloss, bears weak positive correlation with TEWL and skin lesions and weak negative correlation with pH, redness, scales and skin integrity. The study findings suggested that areas having better dermal health are positively correlated with microbial load and biomarker LL-37 and HBD 2,3. Dermal health is a consequence of normal flora and antimicrobial peptides can be used in human skin ointments for treatment of skin disorders.


Keywords: Biochemical characterization, Biomarkers, Biophysical parameters, Dermal health, Microflora, Skin
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How to cite this article:

Sonia Sharma, Alka Sagar, Saurabh Singh Yadav, Pramod W. Ramteke. 2020. Correlation of Biomarker and Biophysical Parameters with Microflora at Different Skin Sites in Young Women (20-21yrs.) of Meerut.Int.J.Curr.Microbiol.App.Sci. 9(2): 1076-1088. doi: https://doi.org/10.20546/ijcmas.2020.902.126