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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(1): 1086-1092
DOI: https://doi.org/10.20546/ijcmas.2020.901.123


Spread of Hepatitis E Viral Infection among Hemodialysis Patients in Pazardzhik District, Bulgaria
Pishmisheva Mariya1, Shikov Peter2, Golkocheva-Markova Еliza3, Kotsev Stanislav1, Naseva Emilia4, Vatev Nikolai5 and Argirova Radka6*
1Dept. Infectious Diseases, Regional Hospital – Pazardzhik, Bulgaria
2Dept. Nephrology and Hemodialysis, Regional Hospital – Pazardik, Bulgaria
3National Reference Laboratory of Viral Hepatitis, National Center of Infectious and Parasitic Diseases, Sofiaq Bulgaria
4Faculty of Public Health, Medical University, Sofia, Bulgaria
5Faculty of Public Health, Medical University, Plovdiv, Bulgaria
6Clinical Laboratory, Dept. of Immunology and Molecular Diagnostics,
Acibadem City Clinic, Tokuda Hospital, Sofia, Bulgaria
*Corresponding author
Abstract:

Hepatitis E virus is the major cause of non A enteral hepatitis. It is usually transmitted by fecal oral route, but infection is possible after bloodproducts transfusion and during birth. The medical literature data are controversial whether dialysis patients are at higher risk of infection. The aim of the study was to investigate the distribution of HEV infection (seroprevalence) in hemodialysis patients from Pazardzhik region, Bulgaria. 102 patients (58.8% men and 41.2% - women) on dialysis treatment were tested. The mean age of the men was 58.7 years, of the women – 59.7. We used epidemiological surveillance and serological testing. From the studied patients 14.7% were anti HEV IgA+IgM+IgG positive. The seroprevalence was significantly higher in male gender (p=0.039). The distribution of HEV infection in hemodialysis patients was lower in comparison to general population (14,7% vs.17%). The conclusion stresses on the need of periodic serological testing for Hepatitis E in patients on hemodialysis.


Keywords: hepatitis E viral infection, seroprevalence, hemodialysis treatment
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How to cite this article:

Pishmisheva Mariya, Shikov Peter, Golkocheva-Markova Еliza, Kotsev Stanislav, Naseva Emilia, Vatev Nikolai and Argirova Radka. 2020. Spread of Hepatitis E Viral Infection among Hemodialysis Patients in Pazardzhik District, Bulgaria.Int.J.Curr.Microbiol.App.Sci. 9(1): 1086-1092. doi: https://doi.org/10.20546/ijcmas.2020.901.123