International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
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Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(9): 1120-1137

Clinico Therapeutic Studies on Ascites in Canines
Sachin Kumar Singh1, S. K. Shukla2, Prakash Bhatt2 and A. K. Singh3*
1Udham Singh Nagar Dairy Cooperative Limited, Pithoragarh, Uttarakhand, India
2Department of Veterinary Clinics, Veterinary Clinics, College of Veterinary and Animal Sciences, Govind Ballabh Pant University of Agriculture and Technology, Pantnagar, India
3Department of veterinary medicine, Pantnagar, India
*Corresponding author

A total 18 dogs maintained at different places were screened and included in the study. All the dogs were put through preliminary screening for the presence of ascites and were subjected to thorough clinical examination including detailed physical and clinical investigation with special reference to haemato-biochemical estimation, ultrasonography and radiography. The dogs found positive were subjected to therapeutic study and were further divided into three groups, namely G II, G IIIand G IVcomprising of 6 animals in each group irrespective of their sex, breed and age. Another group i.e., GI comprising of 6 apparently healthy dogs served as negative control during the study period. The dogs in group G1 were treated with Silymarin-7mg/ml orally, G2 group of dogs were treated with syrup containing Tricholine Citrate, Vitamin B12, Inositol, Methyl donors, Selenium, Vitamin E and Biotin in a base enriched with liver extracts whereas dogs in group G3 were treated with Alfalfa, Avena Sativa, Ashwagandha, Acid Phosphoricum, China, Hydrastis Canadensis, Five Phos, total medication 6.35%, in syrup base. The drugs were given @ 2 tsf of syrup for 45 days. In addition to the specific drugs, common ancillary and supportive treatment was also given. On hematological analysis, there was significant decrease in haemoglobin, PCV, lymphocyte and TEC values in ascitic dogs. No significant change was found in eosinophil and basophil count. Hypoproteinemia, hypoalbuminea and hypoglobulinemia with increased ALT, AST, ALP, GGT, TLC, BUN and creatinine levels were main serum biochemical changes recorded in ascitic dogs. Clinical signs and vital parameters were noticed to have improved after treatment in all the three groups but better improvement was noticed in group G1 which was treated with silymarin.

Keywords: Ascites, haemato-biochemical, hypoproteinemia, hypoalbuminea and hypoglobulinemia, therapeutic, cannines
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How to cite this article:

Sachin Kumar Singh, S. K. Shukla, Prakash Bhatt and Singh, A. K. 2019. Clinico Therapeutic Studies on Ascites in Canines.Int.J.Curr.Microbiol.App.Sci. 8(9): 1120-1137. doi: