Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2019) [Effective from January 1, 2019]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(7): 2794-2799
DOI: https://doi.org/10.20546/ijcmas.2019.807.349


Klebsiella pneumoniae: Prevalence of ESBL Producing Clinical Isolates and their Antimicrobial Susceptibility Pattern in a Hospital Setting
B. Sandya Gnana Sailaja and A. Heraman Singh*
Department of Microbiology, GSL Medical College, Rajahmundry - 533296, India
*Corresponding author
Abstract:

The incidence of infections caused by multidrug resistant ESBL producing K.pneumoniae is on rise. The treatment of these infections have become increasingly difficult and life threatening. Knowledge on prevalence of these infections and corresponding antimicrobial susceptibility patterns is essential regionally. Routine standard operative procedures were followed in the laboratory in processing the clinical specimens for culture and sensitivity. ESBL producing K.pneumoniae were identified by phenotypic combination disc test. Majority of K.pneumoniae were isolated from respiratory specimens and pus, followed by urine and blood respectively. 42 (40.38%) isolates were confirmed as ESBL producing K.pneumoniae. The resistance demonstrated to 3rd generation cephalosporins was significant and to non β lactam antibiotics was moderate. Resistance exhibited to piperacillin/tazobactam was low and nil to carbapenems. The infections caused by multidrug resistant ESBL producing K.pneumoniae are significant. Due to their multidrug resistant nature the treatment options available are limited. Therefore, active surveillance and appropriate infection control measures are necessary to control the spread of these pathogens.


Keywords: ESBL producing K.pneumoniae, cephalosporins, piperacillin/tazobactam, carbapenems
Download this article as Download

How to cite this article:

Sandya Gnana Sailaja, B and Heraman Singh, A. 2019. Klebsiella pneumoniae: Prevalence of ESBL Producing Clinical Isolates and Their Antimicrobial Susceptibility Pattern in a Hospital Setting.Int.J.Curr.Microbiol.App.Sci. 8(7): 2794-2799. doi: https://doi.org/10.20546/ijcmas.2019.807.349