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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(7): 2783-2792
DOI: https://doi.org/10.20546/ijcmas.2019.807.340


Fluid Resuscitation Guided by Stroke Volume Variation in Septic Shock
Roeya Mohamoud Aboelnasr1, Asmaa Fawzy Amer2, Raghda Ghonimy Elsheikh3, Ghada Fouad ELbaradey2 and Sohair Mostafa Soliman2
1Department of Emergency Medicine and Traumatology,
2Department of Anesthesia and Surgical Intensive Care,
3Department of Cardiovascular Medicine, Tanta University Faculty of Medicine, Elgeish Street, Tanta, Gharbia Governorate, Egypt
*Corresponding author
Abstract:

This study was done to evaluate fluid resuscitation guided by stroke volume variation in septic shock. This prospective randomized included sixty patients presented with hypotension (MAP less than 65 mmHg) and hyperlactatemia (serum lactate above 2 mmol/L) in intensive care unit (ICU). Patients were randomly classified into two groups, 30 patients for each group; group I (Early-goal-directed-therapy group {EGDT}) and group II (stroke volume variation guided fluid resuscitation). In group I mortality rate was 33.33% in comparison to 23.33% in group II with no statistically significant difference between two groups. As regard SOFA score, there was statistically significant decrease in 72 hours SOFA score in group II than in group I. Comparing fluid given between two groups showed highly significant increase in amount of fluid in group I than group II. Incorporation of echocardiography early in management of septic shock patients resulted in decrease in the amount of fluid and decrease useless administration of inotropes, early administration of inotropes after assessment of cardiac function by echocardiography which could help in improvement of septic shock outcomes and early vasopressor administration.


Keywords: Septic shock, Echocardiography, Early goal directed therapy, End points of resuscitation
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How to cite this article:

Roeya Mohamoud Aboelnasr, Asmaa Fawzy Amer, Raghda Ghonimy Elsheikh, Ghada Fouad ELbaradey and Sohair Mostafa Soliman. 2019. Fluid Resuscitation Guided by Stroke Volume Variation in Septic Shock.Int.J.Curr.Microbiol.App.Sci. 8(7): 2783-2792. doi: https://doi.org/10.20546/ijcmas.2019.807.340