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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(7): 2323-2329
DOI: https://doi.org/10.20546/ijcmas.2019.807.284


Evaluation of Antifungal Activity of Curcumin against Aspergillus flavus
Anwesha Gitika1⃰, Rajashree Mishra1, Susen Kumar Panda2, Chinmoy Mishraand Pravas Ranjan Sahoo4
1Department of Veterinary Microbiology,
2Department of Veterinary Pathology,
3Department of Animal Breeding and Genetics,
4Department of Veterinary Biochemistry, College of Veterinary Science and Animal Husbandry, OUAT, Bhubabeswar, India
*Corresponding author
Abstract:

The present study was undertaken to study the antifungal effect of curcumin and other synthetic antifungal agents against Aspergillus species isolated from poultry feed. During this study poultry feeds collected from poultry farm of Odisha Veterinary College. Various concentrations of curcumin like 25mg/disc, 50mg/disc, 100mg/disc and 200mg/disc were prepared and were tested by disc diffusion method. In this method antifungal activity of various agents like ketoconazole, voriconazole, itraconazole, clotrimazole, Amphotericin B, miconazole, caspofungin, fluconazole were tested and its zone of inhibition was found to be approximately ≥ 18 mm, ≥ 15mm, ≥ 16mm, ≥ 18mm, ≥ 7 mm, ≥ 10mm, ≥ 18 mm and≥ 10mm respectively. It has been revealed that curcumin treated Aspergillus species showed lesser zone of inhibition than synthetic antifungals like ketoconazole, voriconazole, itraconazole, clotrimazole Amphotericin B, caspofungin but in comparison to fluconazole and miconazole curcumin shows larger zone of inhibition. The antifungal sensitivity pattern shows that curcumin (200 mg/disc) has got the highest potential of antifungal action against A. flavus and A. fumigatus in comparison to synthetic antifungals.


Keywords: Curcumin, Aspergillus species, Antifungal action, Poultry
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How to cite this article:

Anwesha Gitika, Rajashree Mishra, Susen Kumar Panda, Chinmoy Mishra and Pravas Ranjan Sahoo. 2019. Evaluation of Antifungal Activity of Curcumin against Aspergillus flavus.Int.J.Curr.Microbiol.App.Sci. 8(7): 2323-2329. doi: https://doi.org/10.20546/ijcmas.2019.807.284