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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(7): 853-860
DOI: https://doi.org/10.20546/ijcmas.2019.807.102


Urinary Tract Infection: Bacteriological Profile and Its Antibiotic Susceptibility Pattern in a Tertiary Care Hospital in Bangalore
P.R. Lyra, Vivek Hittinahalli* and K.T. Sangeetha
Department of Microbiology, East Point College of Medical Sciences and Research Centre, Bangalore, Karnataka, India
*Corresponding author
Abstract:

Urinary tract infection (UTI) is one of the most common bacterial illnesses and hence one of the most important indications for antibiotic treatment. Current knowledge of the common organisms implicated in causing UTI in the local community and surveillance to monitor the changes in susceptibility of uropathogens are imperative to ensure appropriate therapy. The study objectives were to assess the proportion of UTI caused by each of the common urinary pathogens, to study the antibiotic drug sensitivity patterns by analyzing the culture and sensitivity reports and to identify the drugs which would be potentially favourable candidates for empirical therapy in the study locale. A total of 210 culture positive bacterial isolates from 514 urine samples; submitted over a period of 6 months were included in this study. Identification of bacterial isolates was done by standard biochemical profile of the organisms. The antimicrobial susceptibility of culture positive bacterial isolates was performed by disk diffusion method as recommended by Clinical Laboratory Standard Institute guidelines (CLSI). The predominant organism isolated was E. coli (51.5%) followed by Klebsiella spp (25%) and Pseudomonas spp (14%). Among the 210 samples which yielded growth 150 (71.4%) were from females and 60 (28.6%) were from males. 160 (76%) samples were from inpatients whereas 50 (24%) samples were from outpatients. The susceptibility pattern of E. coli showed that 100 % of the bacterial isolates were sensitive to imipenem and meropenem, 95 % to piperacillin –tazobactam and 92% to nitrofurantoin. Klebsiella spp. showed 100 % sensitivity to imipenem and meropenem followed by piperacillin – tazobactam and amikacin. In conclusion majority of the bacterial isolates were sensitive to imipenem, meropenem, and piperacillin/tazobactam while susceptibility to cephalosporins was very low. Among the oral antimicrobials, nitrofurantoin showed good susceptibility against Enterobacteriaceae family.


Keywords: Enterobacteriaceae, Piperacillin/ tazobactam, Klebsiella spp.
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How to cite this article:

Lyra, P.R., Vivek Hittinahalli and Sangeetha, K.T. 2019. Urinary Tract Infection: Bacteriological Profile and Its Antibiotic Susceptibility Pattern in a Tertiary Care Hospital in Bangalore.Int.J.Curr.Microbiol.App.Sci. 8(7): 853-860. doi: https://doi.org/10.20546/ijcmas.2019.807.102