Staphylococcus aureus and Pseudomonas aeruginosa. This soap was developed by incorporation hexane extract of M. morindoides as antimicrobial agent in formula of basic soap (soap without extract). Minimum inhibitory and bactericidal concentrations (MIC and MBC) of soap "MORINDA" and basic soap against the two above bacteria strains were determined by agar both dilution and plate methods. The results showed high bactericidal activity of soap "MORINDA" against two strains tested with same values of MIC and MBC of 31.25 mg/mL. Basic soap presented the lower bactericidal effect with MIC of 62.50 mg/mL for the two strains tested and MBC of 125.00 mg/mL and 62.50 mg/mL respectively for S. aureus and P. aeruginosa. Comparatively to control soap, hexane extract of M. morindoides gave to soap "MORINDA" effectiveness bactericidal power against these two bacteria involved in cutaneous infections. This study corroborate our previous investigations which showed antifungal activity of this soap and high antibacterial activity of hexane extract of M. morindoides." /> Antibacterial Activity of Soap containing Hexane Extract of Leaves of <em>Morinda morindoides</em> (Morinda; <em>Rubiaceae</em>) against <em>Staphylococcus aureus </em>and <em>Pseudomonas aeruginosa</em>
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Int.J.Curr.Microbiol.App.Sci.2017.6(1): 512-517
DOI: http://dx.doi.org/10.20546/ijcmas.2017.601.061


Antibacterial Activity of Soap containing Hexane Extract of Leaves of Morinda morindoides (Morinda; Rubiaceae) against Staphylococcus aureus and Pseudomonas aeruginosa

Toure Abdoulaye1,2*, Konan Kouakou Severin1,2, Coulibaly Bakary2,3,Ouattara Karamoko2 and Coulibaly Adama2

1Laboratoire de Biotechnologie et Valorisation des Agroressources-UFR Sciences Biologiques, Universite Peleforo GON COULIBALY a  Korhogo, 1328 Korhogo, Cote dIvoire.
2Laboratoire de Pharmacodynamie Biochimique-UFR Biosciences, Universite Felix HOUPHOUET BOIGNY a Cocody-Abidjan, 22 BP 582, Abidjan 22, Cote dIvoire
3Departement de Biochimie-Microbiologie-UFR Agroforesterie, Université Jean LOROUGNON GUEDE a Daloa, BP 150 Daloa, Cote dIvoire.
*Corresponding author
Abstract:

The objective of this study was to perform antibacterial activity of soap containing hexane extract of leaves of Morinda morindoides (Baker) Milne-Redh (Rubiaceae) codified "MORINDA" against Staphylococcus aureus and Pseudomonas aeruginosa. This soap was developed by incorporation hexane extract of M. morindoides as antimicrobial agent in formula of basic soap (soap without extract). Minimum inhibitory and bactericidal concentrations (MIC and MBC) of soap "MORINDA" and basic soap against the two above bacteria strains were determined by agar both dilution and plate methods. The results showed high bactericidal activity of soap "MORINDA" against two strains tested with same values of MIC and MBC of 31.25 mg/mL. Basic soap presented the lower bactericidal effect with MIC of 62.50 mg/mL for the two strains tested and MBC of 125.00 mg/mL and 62.50 mg/mL respectively for S. aureus and P. aeruginosa. Comparatively to control soap, hexane extract of M. morindoides gave to soap "MORINDA" effectiveness bactericidal power against these two bacteria involved in cutaneous infections. This study corroborate our previous investigations which showed antifungal activity of this soap and high antibacterial activity of hexane extract of M. morindoides.


Keywords: Morinda morindoides, hexane extract, soap, antibacterial activity, Côte d’Ivoire.
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How to cite this article:

Toure Abdoulaye, Konan Kouakou Severin, Coulibaly Bakary, Ouattara Karamoko and Coulibaly Adama. 2017. Antibacterial Activity of Soap containing Hexane Extract of Leaves of Morinda morindoides (Morinda; Rubiaceae) against Staphylococcus aureus and Pseudomonas aeruginosa.Int.J.Curr.Microbiol.App.Sci. 6(1): 512-517. doi: http://dx.doi.org/10.20546/ijcmas.2017.601.061