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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2019.8(3): 1258-1268
DOI: https://doi.org/10.20546/ijcmas.2019.803.149


Drug Resistance in an Organisms of Diabetic Foot Patients attending Tertiary Care Hospital in Kulasekharam
K. Greesh and R. Nepolean*
Vasantha Bavanam, Sastha Nagar Main Road, Ashramam, Suchindrum 629 701, Kanyakumari Dist, Tamilnadu, India
*Corresponding author
Abstract:

Diabetes mellitus is a metabolic disorder characterised by chronic glycemia1Twenty five percent diabetic patients have a risk of developing foot ulcer and limp amputation was 15-45%higher than non diabetic ulcer2.Aims: To determine the antibiotic resistance pattern of diabetic foot isolates. A total of 75 specimens (pus, swab, aspirated pus, debridement tissue) were collected from diabetic ulcer patients and the specimens processed by manually. Majority of patients (80%) were in the age group of 51to70 years. The aerobic pathogens isolated were predominantely gram negative (79) and gram positive (28) bacteria. Of these 107,70 gram negative bacilli and 20 gram positive cocci were isolated in the age group between 51 to 70 years. Of 70 gram negative bacilli Pseudomonas species was the predominant, among the gram positive cocci Staphylococcus aureus was predominant. In most of the infections in the age group between 51 to 70 years, it was polymicrobial. The antibiogram of the isolates showed that most of the Pseudomonas species was resistant to 3rd generation cephalosporins (74%), quinolones (76.9%).Klebsiella species 100% resistant to amoxicillin and majority of them also resistant to 3rd generation cephalosporins, E. coli showed high amount of resistance to amoxicillin, cefotoxime, piperacillin. Citrobacter species showed 100% resistant to amoxicillin, cefuroxime, cephalexin. Acinetobacter species showed 100% resistant to amoxicillin, 3rd generation cephalosporins, meropenem, ciprofloxacin, gentamicin. Staphlococcus aureus 100% sensitivity to vancomycin, chloramphenicol, novobiocin.


Keywords: Drug resistance, Diabetic foot patients, Gram negative, cephalosporins
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How to cite this article:

Greesh, K. and Nepolean, R. 2019. Drug Resistance in an Organisms of Diabetic Foot Patients attending Tertiary Care Hospital in Kulasekharam.Int.J.Curr.Microbiol.App.Sci. 8(3): 1258-1268. doi: https://doi.org/10.20546/ijcmas.2019.803.149